Today's pre-market stock movers: CLVS, PATH, DARE and more

• $Clovis Oncology (CLVS.US)$ +40.6% (Rubraca significantly improves progression-free survival in first-line maintenance treatment in women with ovarian cancer regardless of their biomarker status in phase 3 athena-mono trial)

• $Dare Bioscience (DARE.US)$ +13.61% (Organon and Dar Bioscience have entered into an agreement whereby Organon will license global rights to XACIATO)

• $KULR Technology (KULR.US)$ +9.5% (secured a battery safety contract with NASA to test its lithium-ion cells going into future battery packs designed for the Artemis Program)

• $Vipshop (VIPS.US)$ +6.62% (authorizes $1 bln share repurchase program over the next 24-month period)

• $Mainz Biomed (MYNZ.US)$ +6.8% (completes successful pre-submission process with the FDA for ColoAlert's Pivotal Clinical Trial)

• $PROG Holdings (PRG.US)$ +6% (to move to S&P Small Cap 600 from S&P MidCap 400)

• $Orion SA (OEC.US)$ +4.9% (to raise rubber carbon black prices in Europe)

• $Weibo (WB.US)$ +4% (approves share repurchase of up to $500 mln ADS)

• $Corcept Therapeutics (CORT.US)$ +3.4% (presents results from Phase 2 study of relacorilant plus nab-paclitaxel)

• $Core & Main (CNM.US)$ +2.8% (upgraded to Overweight from Equal Weight at Barclays)

• $Five Below (FIVE.US)$ +2.4% (upgraded to Buy from Neutral at Citigroup)

• $CDW Corp (CDW.US)$ +1.9% (upgraded to Overweight from Equal-Weight at Morgan Stanley)

• $UiPath (PATH.US)$ -19.11%, $Expensify (EXFY.US)$ -9.0%, $Masimo (MASI.US)$ -9.4%, $Phreesia (PHR.US)$ -9.12%, $Sharecare (SHCR.US)$ -16.06%, $Tempur Sealy International (TPX.US)$ -6.04%.

• $iQIYI (IQ.US)$ -10.9% $Hutchmed (China) (HCM.US)$ -1.3% $JD.com (JD.US)$ -2.4% $Baidu (BIDU.US)$ -2.4%

• $Fiesta Restaurant (FRGI.US)$ -7.4% (to be removed from S&.P SmallCap 600)

• $Amylyx Pharmaceuticals (AMLX.US)$ -22.9% (FDA advisory committee votes 6-4 for "no" on effectiveness of AMX0035 for the treatment of ALS)

• $Modiv Industrial (MDV.US)$ -5.5% (files for $200 mln mixed securities shelf offering)

• $Bolt Biotherapeutics (BOLT.US)$ -2.5% (files for $250 mln mixed securities shelf offering)

• $HP Inc (HPQ.US)$ -4% (downgraded to Underweight from Equal-Weight at Morgan Stanley)

• $Dell Technologies (DELL.US)$ -3.3% (downgraded to Equal-Weight from Overweight at Morgan Stanley)

• $Advanced Micro Devices (AMD.US)$ -2.3% (downgraded to Equal Weight from Overweight at Barclays)

• $Hub Group (HUBG.US)$ -0.9% (downgraded to Equal-Weight from Overweight at Stephens)