$Cytokinetics (CYTK.US)$ Cytokinetics (CYTK) and Bayer have ...

Cytokinetics (CYTK) and Bayer have established an exclusive licensing agreement for aficamten in Japan, focusing on treating hypertrophic cardiomyopathy (HCM). The deal includes an upfront payment of €50 million to Cytokinetics, with potential additional earnings of €90 million in milestones through commercial launch (including €20 million near-term) and up to €490 million in commercial milestone payments. The collaboration involves tiered royalties on Japanese sales and joint development plans, with Bayer conducting Phase 3 trials for obstructive HCM in Japan while Cytokinetics expands its ACACIA-HCM and CEDAR-HCM trials into the region.