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Unicycive Therapeutics Delivers Multiple Presentations on Oxylanthanum Carbonate (OLC) and UNI-494 at the European Renal Association Congress
Unicycive Therapeutics presented data on its two product candidates, oxylanthanum carbonate (OLC) and UNI-494, at the European Renal Association Congress on May 28, 2024. OLC demonstrated a three-fold greater phosphate lowering capacity compared to tenapanor in a preclinical model of CKD, showing its potential as a treatment for hyperphosphatemia. UNI-494, an ATP-sensitive mitochondrial potassium channel activator, showed significant reduction in important markers for acute kidney injury (AKI) in a preclinical model, indicating its potential for preventing delayed graft function (DGF). Additionally, ongoing clinical trials for both products were highlighted with results expected later in the year.
Unicycive Therapeutics presented data on its two product candidates, oxylanthanum carbonate (OLC) and UNI-494, at the European Renal Association Congress on May 28, 2024. OLC demonstrated a three-fold greater phosphate lowering capacity compared to tenapanor in a preclinical model of CKD, showing its potential as a treatment for hyperphosphatemia. UNI-494, an ATP-sensitive mitochondrial potassium channel activator, showed significant reduction in important markers for acute kidney injury (AKI) in a preclinical model, indicating its potential for preventing delayed graft function (DGF). Additionally, ongoing clinical trials for both products were highlighted with results expected later in the year.
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