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Replimune Presents Positive Data from RP1 and RP2 Clinical Programs at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting
Replimune presented positive data from its RP1 and RP2 clinical programs at the 2024 ASCO Annual Meeting. The IGNYTE trial showed a 32.7% overall response rate (ORR) for RP1 plus nivolumab in anti-PD-1 failed melanoma, with responses lasting over six months and a median duration exceeding 36 months. RP2, both as monotherapy and in combination with nivolumab, achieved an ORR of nearly 30% in uveal melanoma. The company plans a registration-directed trial for RP2 and will submit a Biologics License Application for RP1 in the second half of 2024. These results indicate a promising risk-benefit profile, particularly in hard-to-treat cancers.
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