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TriSalus Announces Journal of Vascular and Interventional Radiology Publication of Data that Demonstrate Improved Therapeutic Delivery of Glass Microspheres to Solid Tumors With PEDD™ Method via the TriNav® Infusion System
TriSalus Life Sciences (Nasdaq: TLSI) announced the publication of research in the Journal of Vascular and Interventional Radiology demonstrating improved delivery of glass microspheres to liver tumors using their Pressure Enabled Drug Delivery (PEDD) methodvia the TriNav Infusion System. The study, conducted on transgenic pigs with induced liver tumors, showed:
- 117% increase in tumor penetration with lobar infusions (p=0.004)
- 39% increase in tumor penetration with selective infusions (p=0.032)
- Lobar PEDD delivery was statistically equivalent to conventional selective delivery (p=0.497)
The research suggests that the PEDD method could potentially improve the efficacy and safety of liver cancer treatments by increasing the concentration of therapeutics in tumors compared to adjacent liver tissue.
- 117% increase in tumor penetration with lobar infusions (p=0.004)
- 39% increase in tumor penetration with selective infusions (p=0.032)
- Lobar PEDD delivery was statistically equivalent to conventional selective delivery (p=0.497)
The research suggests that the PEDD method could potentially improve the efficacy and safety of liver cancer treatments by increasing the concentration of therapeutics in tumors compared to adjacent liver tissue.
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