NEWS
Invivyd Provides Detailed Virology Data and Analysis of SARS-CoV-2 Structural Biology Predicting Anticipated Neutralization Activity for PEMGARDA™ (pemivibart)
Invivyd, Inc. (Nasdaq: IVVD) has provided detailed virology data and analysis of SARS-CoV-2 structural biology, predicting anticipated neutralization activity for PEMGARDA™ (pemivibart). Key points include:
Independent evaluation shows in vitro pseudovirus neutralization potency of PEMGARDA against KP.3.1.1 and LB.1 variants in-line with prior variants tested
Ongoing SARS-CoV-2 spike analyses demonstrate consistent structural stability of the pemivibart binding site
Potential emerging variants (XEC and LP.1) encode mutations distal from the pemivibart binding site, not expected to meaningfully alter activity
Pemivibart potency against contemporary viruses remains in-line with predominant variants since 2022
Structural analysis shows no meaningful mutational change in the pemivibart binding site since late 2021
The company's ongoing genetic and structural analyses provide the biological rationale for expected neutralization activity of pemivibart against evolving SARS-CoV-2 variants.
Independent evaluation shows in vitro pseudovirus neutralization potency of PEMGARDA against KP.3.1.1 and LB.1 variants in-line with prior variants tested
Ongoing SARS-CoV-2 spike analyses demonstrate consistent structural stability of the pemivibart binding site
Potential emerging variants (XEC and LP.1) encode mutations distal from the pemivibart binding site, not expected to meaningfully alter activity
Pemivibart potency against contemporary viruses remains in-line with predominant variants since 2022
Structural analysis shows no meaningful mutational change in the pemivibart binding site since late 2021
The company's ongoing genetic and structural analyses provide the biological rationale for expected neutralization activity of pemivibart against evolving SARS-CoV-2 variants.
Disclaimer: Community is offered by Moomoo Technologies Inc. and is for educational purposes only.
Read more
Comment
Sign in to post a comment
Spread kindness and love. Life is short. Don’t let greed eat you.
2018Followers
102Following
17KVisitors
Follow