Rallybio (Nasdaq: RLYB) will present full data from an epidemiological analysis at the American Society of Human Genetics (ASHG) 2024 Annual Meetingin Denver, CO. The analysis quantifies the proportion of women across diverse populations at higher risk of a fetal and neonatal alloimmune thrombocytopenia (FNAIT)-impacted pregnancy.
Key findings include:
Women at higher risk for FNAIT are more prevalent than previously estimated
Risk extends beyond Caucasian populations
Highest risk found in Ashkenazi Jewish (0.65%), non-Finnish European (0.64%), and Middle Eastern (0.62%) populations
Significant risk also found in Caribbean Hispanic (0.33%) and African/African American (0.28%) populations
The analysis suggests over 30,000 pregnancies annually in North America and major European countries are at higher risk for FNAIT, representing a 40% increase from prior estimates and a $1.6 billion commercial opportunity.