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Phio Pharmaceuticals Presenting Data on Its INSTAYL Compound PH-894 at ASGCT's 2024 Advancing Gene and Cell Therapies for Cancer Conference
Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is presenting data on its INTASYL compound PH-894 at the ASGCT's 2024 Advancing Gene and Cell Therapies for Cancer conference. The presentation focuses on how PH-894 improves the functionality and cytotoxicity of Natural Killer (NK) cells in fighting cancer:
1. PH-894 leads to potent and specific silencing of BRD4 in NK cells without affecting cell viability.
2. It boosts NK cell numbers by enhancing proliferation during ex vivo expansion.
3. PH-894 decreases expression of CD94, an inhibitory receptor, potentially improving cytotoxic potential.
4. It may improve NK cell efficacy in adoptive cell therapies.
5. PH-894 serves as a foundation for future NK cell-based immunotherapies.
The presentation by Melissa Maxwell is scheduled for October 16, 2024, from 8 a.m. to 6:45 p.m. ET in the FDR Ballroom.
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