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SIGA Enters into Exclusive License Agreement with Vanderbilt University for Novel Poxvirus Monoclonal Antibodies
SIGA Technologies (NASDAQ: SIGA) has entered into an exclusive license agreement with Vanderbilt University for a portfolio of preclinical fully human monoclonal antibodies (mAbs). These mAbs have potential as treatments for a broad range of orthopoxviruses, including smallpox and mpox. The agreement grants SIGA exclusive rights to develop, manufacture, and commercialize these mAbs globally.
The mAbs, developed by Dr. James Crowe at Vanderbilt University Medical Center, have shown promise in preclinical models and could be used as standalone treatments or in combination with SIGA's TPOXX® franchise. The U.S. Department of Defense is currently funding the development of these mAbs through Phase 1 clinical trials. SIGA aims to leverage its expertise in orthopoxvirus and partnerships with U.S. Government agencies to maximize the impact of these potential new therapies.
The mAbs, developed by Dr. James Crowe at Vanderbilt University Medical Center, have shown promise in preclinical models and could be used as standalone treatments or in combination with SIGA's TPOXX® franchise. The U.S. Department of Defense is currently funding the development of these mAbs through Phase 1 clinical trials. SIGA aims to leverage its expertise in orthopoxvirus and partnerships with U.S. Government agencies to maximize the impact of these potential new therapies.
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