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Nektar Announces Publication in Nature Communications of Results from Phase 1b Studies of Rezpegaldesleukin in Two Inflammatory Skin Diseases
Nektar Therapeutics (NKTR) published peer-reviewed data from two Phase 1b studies in Nature Communications showing promising results for rezpegaldesleukin in treating atopic dermatitis (AD) and psoriasis (PsO). The studies demonstrated that the drug safely increased regulatory T cells (Tregs) and improved disease outcomes, with effects lasting up to 36 weeks after treatment cessation. High-dose AD patients showed an 83% improvement in EASI score after 12 weeks, with EASI-75 and vIGA-AD responses maintained in 71% and 80% of week 12 responders respectively for 36 weeks post-treatment.
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