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NEWS
Mural Oncology Presents Clinical and Preclinical Data Across its Pipeline at the 39th Annual Meeting of the Society for Immunotherapy of Cancer (SITC)
Mural Oncology presented clinical and preclinical data at the 39th SITC Annual Meeting. The ARTISTRY-3 trial showed that less frequent IV dosing of nemvaleukin demonstrated tumor site-specific immune activation in ovarian cancer and mucosal melanoma patients. Preclinical data from IL-18 variants showed durable immune responses and tumor growth inhibition, with candidate nomination expected by end of 2024 and IND submission in Q4 2025. The company's IL-12 program demonstrated potential to mitigate cytokine toxicity, with candidate nomination planned by end of 2024. Two late-stage trials, ARTISTRY-7 for platinum-resistant ovarian cancer and ARTISTRY-6 for mucosal melanoma, expect data readouts in late Q1/early Q2 2025 and Q2 2025, respectively.
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