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FibroBiologics Files Patent Application Covering Reduction of Blood Clots Associated with Instant Blood-Mediated Inflammatory Reaction (IBMIR) in Cell-Based Therapeutics
FibroBiologics (Nasdaq: FBLG) has filed a patent application for methods using fibroblasts and Tissue Factor-expressing cells to prevent IBMIR-mediated blood clotting in cell therapy treatments. The technology aims to address a major challenge in cell therapy by reducing inflammatory and coagulative responses that can compromise treatment effectiveness and safety. The approach focuses on minimizing complications such as complement activation, immune cell infiltration, and platelet adhesion during intravascular, subcutaneous, and intraperitoneal cell administration. This development could potentially improve the safety and efficacy of cell-based treatments by reducing adverse events and rejection by the body's immune system.
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