-- Achieved all co-primary endpoints of LS mean reduction in LDL-C on top of maximally tolerated lipid-modifying therapies versus each of placebo, ezetimibe 10 mg, and obicetrapib 10 mg monotherapy at day 84 with statistical significance (p<0.001) --
-- Obicetrapib and ezetimibe fixed-dose combination observed to lower LDL-C by approximately 50% at day 84, compared to placebo, with over 70% of patients achieving LDL-C levels below 55 mg/dL --
-- Data supports global regulatory filings of the obicetrapib 10 mg and ezetimibe 10 mg fixed-dose combination --
-- Observed to be well tolerated with safety results in line with prior studies --
-- NewAmsterdam to host conference call today at 8:00 a.m. ET -