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Ensysce Biosciences Completes Significant Milestone, Dosing First Subjects in Breakthrough Therapy PF614-MPAR Trial
Ensysce Biosciences (NASDAQ:ENSC)has initiated dosing in the PF614-MPAR-102 study, marking a significant milestone for its breakthrough therapy-designated opioid drug.
The trial aims to evaluate the pharmacokinetics of oxycodone and PF614 when co-administered with nafamostat.
The study received a $14 million multi-year award from NIDA and expects early interim data in Q1 2025.
The three-part trial will assess the full dosage range, food effects, and conduct multi-ascending dose studies of PF614-MPAR, which is designed to reduce deliberate and accidental overdoses in severe pain treatment.
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