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NEWS
ACELYRIN, INC. Announces Topline Results From Phase 2b/3 Study of Izokibep for the Treatment of Uveitis
ACELYRIN (Nasdaq: SLRN) announced that its Phase 2b/3 trial of izokibep in non-infectious, non-anterior uveitis failed to meet its primary endpoint of showing statistically significant improvement in time to treatment failure versus placebo at 24 weeks. Secondary endpoints also did not achieve statistical significance.
ACELYRIN (Nasdaq: SLRN) announced that its Phase 2b/3 trial of izokibep in non-infectious, non-anterior uveitis failed to meet its primary endpoint of showing statistically significant improvement in time to treatment failure versus placebo at 24 weeks. Secondary endpoints also did not achieve statistical significance.
Following these results and previous guidance, ACELYRIN will discontinue internal investment in izokibep development. The company will focus on advancing lonigutamab for thyroid eye disease (TED), with Phase 3 trials scheduled to begin in Q1 2025. The company reports $562.4 million in cash and equivalents as of September 30, 2024, providing runway until mid-2027.
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Trytosaveabit : A bit of bearish news in there! But overall I think it looks pretty good.
Jaguar8 OP Trytosaveabit : Yes still have something in its pipeline
Jaguar8 OP Trytosaveabit : And lots of cash too
StockRoller : CFO resigns. Bad news?
Trytosaveabit Jaguar8 OP : It may be one of those! Overreaction and able to jump in at bottom and scalp 20/30%? Hehehe
Trytosaveabit Jaguar8 OP : Indeed!
Jaguar8 OP Trytosaveabit : Yes I’m waiting for the crash then scoop the dip
Jaguar8 OP StockRoller : CFO won’t matter much since this company has lots of cash and has no liquidity issue
StockRoller Jaguar8 OP : This?
Trytosaveabit Jaguar8 OP : Agreed! Nicely put my Brother
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