Positive
Completion of Phase 2 study on schedule.
Study funded by the Gates Foundation and Alzheimer’s Association, indicating strong support.
Topline results expected by summer 2024.
Preliminary data showed significant improvements in cognitive function.
Significant enhancement in regulatory T cell (Treg) function and numbers.
No serious adverse events reported in preliminary studies.
No patient discontinued the study.
Negative
Study involved a small number of participants (38 patients).
Results from Phase 2 not yet available; uncertainty remains.
Previous studies were open-label with only 8 patients, limiting generalizability.