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Metagenomi Presents AI-Enabled Advancements of SMART Editing Platform at the Cold Spring Harbor Laboratory CRISPR Frontiers Conference
Metagenomi (Nasdaq: MGX) presented advancements in its AI-enabled SMART Editing Platform at the CRISPR Frontiers Conference. The company showcased AI-generated compact SMART nucleaseswith robust genome editing activity in mammalian cells. These tools, fitting within size-constrained delivery technologies, may enable broader disease targeting.
Key highlights include:
AI-based gene editing variants showing high efficiency in mammalian cells
Compact base editors less than 1,000 amino acids long
De novo, AI-generated synthetic nucleases demonstrating robust activity
Rational engineering achieving saturating levels of editing in human cells
Metagenomi's approach combines its metagenomics database of over 11 billion proteins with AI to create novel gene editing tools, potentially accelerating drug development and opening new therapeutic applications.
Key highlights include:
AI-based gene editing variants showing high efficiency in mammalian cells
Compact base editors less than 1,000 amino acids long
De novo, AI-generated synthetic nucleases demonstrating robust activity
Rational engineering achieving saturating levels of editing in human cells
Metagenomi's approach combines its metagenomics database of over 11 billion proteins with AI to create novel gene editing tools, potentially accelerating drug development and opening new therapeutic applications.
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