北美深蓝 : No need to try to get chestnuts from the fire, just give up.

北美深蓝 : Founders and management received extremely high salaries, not long after going public, clinical failure, handled well.

北美深蓝 101821671 OP : There is a suspicion of quick profit sharing, but the degree of interest binding is not sufficient.

北美深蓝 OP : $Bigtincan Holdings Ltd (BTH.AU)$ An announcement has been made, Bigtincan Holdings Ltd: No counterproposal from Investcorp has been received. The merger came to an end Waiting for the next better target

北美深蓝 OP : $Bigtincan Holdings Ltd (BTH.AU)$ Will pay liquidated damages for early termination.

北美深蓝 OP : The voting gap is too large, the current CEO and management team receive too little support, and the benefit distribution of the merger agreement is not settled.

北美深蓝 OP : Information related to the PREVAIL trial:
The design of the PREVAIL trial refers to the lessons learned from previous CETP inhibitor CVOT failures, using stricter inclusion criteria and longer follow-up time to increase the chances of trial success.
The company expects to announce the PREVAIL trial data in 2026.
As of April 2024, the PREVAIL trial has achieved its recruitment target of 9,000 patients and extended recruitment until the end of April, with over 9,500 patients randomized.
———The purpose of designing the PREVAIL trial by the company is to validate the efficacy of obicetrapib in reducing MACE, support its marketing application, and future market promotion. Once successful, this trial can prove that obicetrapib can bring clinical benefits to ASCVD patients and make it stand out in competition with other lipid-lowering drugs.

北美深蓝 OP : Based on yesterday's declining trading volume (3.01 million shares), short selling ratio (8.07%), and previous trends, combined with the company's previous disclosure of information, it may be an insider trade that complies with the rules planned in advance.
The stock price was raised in a planned manner before the clinical results were disclosed, then the clinical results were disclosed, and then the rules were triggered to sell (or the buyer's chip transfer). The stock price fell, but the magnitude of the decline and price were within the expected range, ending the sell-off and starting the next round of trends.
Due to this decline, the lowest price is higher than the increase price at the beginning of the year.
On March 28, 2024, NAP PoolCo B.V. (“PoolCo”) adopted a 10b5-1 rule trading arrangement that may sell up to 2.95 million shares of the company's common stock, subject to certain price thresholds and other conditions. The purpose of the arrangement is to allow company insiders to sell their company shares without violating insider trading laws. It is estimated that this decline is related to this, and the conditional threshold set may be related to the disclosure of current clinical results.
The following are more references to the 10b5-1 rule and scheduled trading arrangements under this rule:
10b5-1 Rule: The 10b5-1 rule is a rule made by the US Securities and Exchange Commission (SEC) that allows company insiders (such as executives and directors) to trade company shares under a pre-set plan, even if they later obtain insider information. The rule requires insiders not to have any insider information when drawing up a deal plan and must submit it to the SEC before the plan becomes effective.
Trading arrangement: The 10b5-1 rule trading arrangement adopted by PoolCo allows it to sell up to 2.95 million common shares of a company when certain pre-set conditions (such as price thresholds and other conditions, but there are no such details in the company's disclosure).
Purpose: The purpose of this arrangement is to provide PoolCo with a way to sell its company shares without violating insider trading laws. It also helps insiders trade stocks without causing market speculation about their intention to hold shares.
Schedule: Transactions under this arrangement may not commence earlier than 90 days after its adoption or two business days after the submission of Form 10-Q for this quarterly report. The arrangement expires on June 28, 2026.
PoolCo's background: PoolCo is a Dutch limited liability company that holds the company's common shares on behalf of its shareholders and is controlled by Forbion International Management B.V., whose board member Sander Slootweg is one of the directors of Forbion International Management B.V.

北美深蓝 OP : Let's also take a look at the largest holding institution. Since 2023, the net reduction in holdings has been reduced by about 30% in Q3

北美深蓝 OP : I finally fired this CEO

北美深蓝 OP : After President Trump took office, canceling subsidies for electric vehicles will definitely bring negative impact to its important market - the electric vehicle industry, which is one of the bearish indicators, suggesting a decline.

北美深蓝 : Pay attention to the company's assets and liabilities ratio, focus on the interest expenses brought by net debt, the company's net cash flow, and revenue change trends. Do not act impulsively! Dismissing the CEO is also negative news, at least indicating strategic mistakes or delays that have been brought to the company, further observation is needed.