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$Tesla (TSLA.US)$ So, honest question: Has it just been determined by the market that everyone will be forced to buy a Tesla car, forever? Should we just expect that Tesla will overtake the entire US GDP?
Asking for a friend.
Asking for a friend.
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Vaccine makers have thus far been hesitant to tweak existing coronavirus jabs due to fears it could become a game of whack-a-mole, but a super strain may change that sentiment. Testing involving Omicron is already underway among the big manufacturers, with several saying it would take about two weeks to establish whether the new variant renders their shots less effective. On Friday, South Africa's health minister said he expects current jabs to still offer protection against severe illness and death from Omicron, though they might be less effective at preventing infections and milder disease.
In case it doesn't: $Pfizer (PFE.US)$ and partner $BioNTech (BNTX.US)$ said they would be able to adapt their vaccines within six weeks, and ship initial batches within 100 days in the event of an escape variant. Moderna can meanwhile get a new construct into human trials in less than 60 days, though manufacturing would take a few months. Any new candidates would also need to clear the regulatory process, getting a green light from the Food and Drug Administration.
In terms of therapeutics, Pfizer's Paxlovid and $Merck & Co (MRK.US)$ molnupiravir are expected to target parts of the virus that are not changed in Omicron, and could be all the more important if vaccine-induced and natural immunity are threatened. Both drugmakers have licensed their antiviral pills to other manufacturers, so they should be widely available if needed. The Biden administration has even ordered 13M courses of the two drugs after seeing significant success in trials at preventing severe illness in high-risk groups.
Outlook: Regarding manufactured antibodies, Omicron's mutations are likely to render some treatments ineffective, according to Dr. David Ho, professor of microbiology and immunology at Columbia University. Investors are particularly worried about antibody drugs from $Regeneron Pharmaceuticals (REGN.US)$ and $Eli Lilly and Co (LLY.US)$, but some think $Vir Biotechnology (VIR.US)$ and $AstraZeneca (AZN.US)$ could hold up better against this variant due to the way the antibodies are constructed to target the spike proteins. The new variant might also dull the impact of monoclonal antibody treatment because of those same mutations, said Dr. Wendy Barclay, head of the G2P-UK National Virology Consortium.
In case it doesn't: $Pfizer (PFE.US)$ and partner $BioNTech (BNTX.US)$ said they would be able to adapt their vaccines within six weeks, and ship initial batches within 100 days in the event of an escape variant. Moderna can meanwhile get a new construct into human trials in less than 60 days, though manufacturing would take a few months. Any new candidates would also need to clear the regulatory process, getting a green light from the Food and Drug Administration.
In terms of therapeutics, Pfizer's Paxlovid and $Merck & Co (MRK.US)$ molnupiravir are expected to target parts of the virus that are not changed in Omicron, and could be all the more important if vaccine-induced and natural immunity are threatened. Both drugmakers have licensed their antiviral pills to other manufacturers, so they should be widely available if needed. The Biden administration has even ordered 13M courses of the two drugs after seeing significant success in trials at preventing severe illness in high-risk groups.
Outlook: Regarding manufactured antibodies, Omicron's mutations are likely to render some treatments ineffective, according to Dr. David Ho, professor of microbiology and immunology at Columbia University. Investors are particularly worried about antibody drugs from $Regeneron Pharmaceuticals (REGN.US)$ and $Eli Lilly and Co (LLY.US)$, but some think $Vir Biotechnology (VIR.US)$ and $AstraZeneca (AZN.US)$ could hold up better against this variant due to the way the antibodies are constructed to target the spike proteins. The new variant might also dull the impact of monoclonal antibody treatment because of those same mutations, said Dr. Wendy Barclay, head of the G2P-UK National Virology Consortium.
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Do U have problems DianaSun_02 : For those that don't see the sarcasm, the US government has been going out of it way to ignore Tesla. Instead it is going out of its way to praise, subsidize and promote legacy auto makers. Yet tesla is the only company that is making electric vehicles in the US. Lucid is just getting started. It reeks of crony capitalism at its finest.