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CRISPR Therapeutics | 8-K: CRISPR Therapeutics Provides Business Update and Reports Second Quarter 2024 Financial Results

CRISPR Therapeutics | 8-K: CRISPR Therapeutics Provides Business Update and Reports Second Quarter 2024 Financial Results

CRISPR Therapeutics | 8-K:CRISPR Therapeutics提供最新业务并公布2024年第二季度财务业绩
美股SEC公告 ·  2024/08/05 13:09

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CRISPR Therapeutics reported Q2 2024 financial results with a strong cash position of $2 billion as of June 30, 2024. The company has activated more than 35 authorized treatment centers globally for CASGEVY, with approximately 20 patients having cells collected across all regions as of mid-July. CASGEVY is now approved in the US, Great Britain, EU, Saudi Arabia, and Bahrain for both sickle cell disease and transfusion-dependent beta thalassemia.The company continues advancing its pipeline, with clinical trials ongoing for next-generation CAR T products CTX112 and CTX131 across multiple indications. CTX112 trials have expanded into systemic lupus erythematosus, while CTX131 trials now include hematological malignancies. Additionally, in vivo gene editing programs CTX310 and CTX320 targeting cardiovascular diseases are progressing in clinical trials.Q2 financial results showed minimal revenue compared to $70 million in Q2 2023. R&D expenses decreased to $80.2 million from $101.6 million year-over-year. Net loss widened to $126.4 million from $77.7 million in Q2 2023, primarily due to reduced collaboration revenue and increased collaboration expenses related to CASGEVY commercialization.
CRISPR Therapeutics reported Q2 2024 financial results with a strong cash position of $2 billion as of June 30, 2024. The company has activated more than 35 authorized treatment centers globally for CASGEVY, with approximately 20 patients having cells collected across all regions as of mid-July. CASGEVY is now approved in the US, Great Britain, EU, Saudi Arabia, and Bahrain for both sickle cell disease and transfusion-dependent beta thalassemia.The company continues advancing its pipeline, with clinical trials ongoing for next-generation CAR T products CTX112 and CTX131 across multiple indications. CTX112 trials have expanded into systemic lupus erythematosus, while CTX131 trials now include hematological malignancies. Additionally, in vivo gene editing programs CTX310 and CTX320 targeting cardiovascular diseases are progressing in clinical trials.Q2 financial results showed minimal revenue compared to $70 million in Q2 2023. R&D expenses decreased to $80.2 million from $101.6 million year-over-year. Net loss widened to $126.4 million from $77.7 million in Q2 2023, primarily due to reduced collaboration revenue and increased collaboration expenses related to CASGEVY commercialization.
CRISPR Therapeutics报告了2024年第二季度的财务结果,截至2024年6月30日,现金储备为20亿美元。该公司在全球已启动超过35个授权治疗中心用于CASGEVY,截至7月中旬,约有20名患者在所有地区收集了电芯。CASGEVY已获得美国、英国、欧盟、沙特阿拉伯和巴林的批准,用于治疗镰状细胞病和依赖输血的β地中海贫血。该公司继续推进其研发管线,正在进行下一代CAR-t产品CTX112和CTX131的临床试验,涵盖多个适应症。CTX112的试验已扩展至系统性红斑狼疮,而CTX131的试验现在包括血液恶性肿瘤。此外,针对心血管疾病的体内基因编辑项目CTX310和CTX320也在临...展开全部
CRISPR Therapeutics报告了2024年第二季度的财务结果,截至2024年6月30日,现金储备为20亿美元。该公司在全球已启动超过35个授权治疗中心用于CASGEVY,截至7月中旬,约有20名患者在所有地区收集了电芯。CASGEVY已获得美国、英国、欧盟、沙特阿拉伯和巴林的批准,用于治疗镰状细胞病和依赖输血的β地中海贫血。该公司继续推进其研发管线,正在进行下一代CAR-t产品CTX112和CTX131的临床试验,涵盖多个适应症。CTX112的试验已扩展至系统性红斑狼疮,而CTX131的试验现在包括血液恶性肿瘤。此外,针对心血管疾病的体内基因编辑项目CTX310和CTX320也在临床试验中不断推进。第二季度财务结果显示,与2023年第二季度的7000万美元相比,营业收入微乎其微。研发费用从去年的10160万美元降至8020万美元。净亏损从2023年第二季度的7770万美元扩大至12640万美元,主要是由于CASGEVY商业化相关的协作收入减少和协作费用增加。
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