Gainers

• Avalo Therapeutics (NASDAQ:AVTX) shares rose 17.3% to $3.53 during Wednesday's regular session. The company's market cap stands at $46.5 million.
• Journey Medical (NASDAQ:DERM) shares rose 15.59% to $1.84. Trading volume for this security as of 13:30 EST is 55.9K, which is 228.4% of its average full-day volume over the last 100 days. The company's market cap stands at $33.3 million.
• Societal CDMO (NASDAQ:SCTL) shares rose 15.14% to $0.9. Trading volume for Societal CDMO's stock is 81.4K as of 13:30 EST. This is 43.5% of its average full-day volume over the last 100 days. The company's market cap stands at $76.2 million.
• Microbot Medical (NASDAQ:MBOT) stock moved upwards by 14.79% to $2.56. The current volume of 1.5 million shares is 44.6% of Microbot Medical's average full-day volume over the last 100 days (last updated at 13:30 EST). The market value of their outstanding shares is at $24.9 million.
• Mereo BioPharma Group (NASDAQ:MREO) shares moved upwards by 14.78% to $1.32. Trading volume for Mereo BioPharma Group's stock is 3.3 million as of 13:30 EST. This is 194.0% of its average full-day volume over the last 100 days. The company's market cap stands at $164.9 million.
• Oncology Institute (NASDAQ:TOI) stock rose 14.78% to $0.47. Trading volume for this security as of 13:30 EST is 289.6K, which is 108.5% of its average full-day volume over the last 100 days. The company's market cap stands at $35.4 million.

Losers

• PolarityTE (NASDAQ:PTE) shares declined by 43.1% to $0.25 during Wednesday's regular session. PolarityTE's stock is trading at a volume of 2.0 million shares as of 13:30 EST. This is 2960.1% of its average full-day volume over the last 100 days. The market value of their outstanding shares is at $1.8 million.
• Vaxart (NASDAQ:VXRT) stock decreased by 28.3% to $0.89. As of 13:30 EST, this security is trading at a volume of 8.3 million shares, making up 547.3% of its average full-day volume over the last 100 days. The market value of their outstanding shares is at $120.5 million.
• Allarity Therapeutics (NASDAQ:ALLR) stock decreased by 20.05% to $0.19. Trading volume for this security as of 13:30 EST is 3.0 million, which is 91.7% of its average full-day volume over the last 100 days. The company's market cap stands at $3.5 million.
• NewAmsterdam Pharma (NASDAQ:NAMS) stock decreased by 16.16% to $11.55. Trading volume for NewAmsterdam Pharma's stock is 429.0K as of 13:30 EST. This is 1273.7% of its average full-day volume over the last 100 days. The company's market cap stands at $944.4 million.
• CARISMA Therapeutics (NASDAQ:CARM) stock fell 16.01% to $6.09. Trading volume for CARISMA Therapeutics's stock is 289.3K as of 13:30 EST. This is 160.4% of its average full-day volume over the last 100 days. The market value of their outstanding shares is at $245.1 million.
• HTG Molecular Diagnostics (NASDAQ:HTGM) shares decreased by 13.78% to $0.76. Trading volume for this security as of 13:30 EST is 449.6K, which is 218.1% of its average full-day volume over the last 100 days. The company's market cap stands at $1.6 million. See Also:

This article was generated by Benzinga's automated content engine and reviewed by an editor.