share_log

BullFrog AI's Collaboration With Lieber Institute for Brain Development Yields Potentially Groundbreaking Biological Stratification of Brain Expression Data

BullFrog AI's Collaboration With Lieber Institute for Brain Development Yields Potentially Groundbreaking Biological Stratification of Brain Expression Data

BullFrog AI 与利伯大脑发育研究所的合作有可能对大脑表达数据进行突破性的生物分层
GlobeNewswire ·  01/17 07:00

GAITHERSBURG, Md., Jan. 17, 2024 (GLOBE NEWSWIRE) -- BullFrog AI Holdings, Inc. (NASDAQ: BFRG; BFRGW) ("BullFrog AI" or the "Company"), a technology-enabled drug development company using artificial intelligence (AI) and machine learning to enable the successful development of pharmaceuticals and biologics, today announced early results from its collaboration with the Lieber Institute for Brain Development (LIBD) that could revolutionize the understanding and treatment of psychiatric disorders. The early findings from this global strategic partnership have successfully stratified brain expression data, offering what may turn out to be unprecedented insights into psychiatric conditions.

马里兰州盖瑟斯堡,2024年1月17日(GLOBE NEWSWIRE)——BullFrog AI Holdings, Inc.(纳斯达克股票代码:BFRG;BFRGW)(“BullFrog AI” 或 “公司”)是一家利用人工智能(AI)和机器学习实现药物和生物制剂成功开发的技术型药物开发公司,今天公布了与利伯大脑研究所合作的初步成果开发(LIBD)可能会彻底改变对精神疾病的理解和治疗。这一全球战略伙伴关系的早期发现成功地对大脑表达数据进行了分层,为精神疾病提供了前所未有的见解。

"This collaboration marks a pivotal moment in psychiatric research," said Vin Singh, CEO of BullFrog AI. "By employing our bfLEAP platform on LIBD's unrivaled brain data, we've gained invaluable ground into unraveling the biological underpinnings of psychiatric disorders. These preliminary findings have the potential to not only deepen our understanding but also pave the way for developing more targeted and effective treatments that set the stage for us to seek out revenue-generating strategic partnerships with pharmaceutical companies."

BullFrog AI首席执行官文·辛格说:“这次合作标志着精神病学研究的关键时刻。”“通过在LIBD无与伦比的大脑数据上使用我们的bFleap平台,我们在揭示精神疾病的生物学基础方面取得了宝贵的基础。这些初步发现不仅有可能加深我们的理解,而且有可能为开发更具针对性和更有效的治疗方法铺平道路,为我们寻求与制药公司建立创收战略合作伙伴关系奠定基础。”

The proprietary data from LIBD included gene expression data from over 2,800 brain samples encompassing schizophrenia, bipolar disorder, major depressive disorder, and non-psychiatric control brains. Utilizing graph analytics, BullFrog AI and LIBD have, for the first time, clustered subjects based solely on their biological data, independent of their behavioral diagnoses. This innovative approach has yielded promising insights, highlighting distinct differences and similarities in biological pathways across various brain disorders. Moreover, it has revealed biological subtypes within individual disorders, offering a nuanced understanding that could lead to personalized treatment strategies.

来自LIBD的专有数据包括来自2,800多个大脑样本的基因表达数据,包括精神分裂症、躁郁症、重度抑郁症和非精神控制大脑。利用图表分析,BullFrog AI和LIBD首次仅根据受试者的生物学数据对受试者进行聚类,而与其行为诊断无关。这种创新的方法产生了令人鼓舞的见解,突显了各种脑部疾病的生物通路的明显差异和相似之处。此外,它还揭示了个体疾病中的生物亚型,提供了细致入微的理解,可以制定个性化的治疗策略。

Daniel R. Weinberger, M.D., Director and CEO of LIBD, added, "Our collaboration with BullFrog AI has enabled us to apply cutting-edge AI technologies to our extensive brain data. The preliminary results are provocative and offer novel insights at the gene level that may only be discoverable using these novel AI technologies, offering a new lens through which we can view and potentially treat brain disorders. This is an important first step towards personalized medicine in psychiatry."

LIBD董事兼首席执行官Daniel R. Weinberger医学博士补充说:“我们与BullFrog AI的合作使我们能够将尖端的人工智能技术应用于大量的大脑数据。初步结果具有挑衅性,在基因层面提供了新的见解,只有使用这些新的人工智能技术才能发现这些见解,为我们提供了一个新的视角,我们可以通过它来观察并有可能治疗脑部疾病。这是迈向精神病学个性化医疗的重要第一步。”

The market opportunity for new treatments in psychiatric disorders is vast and underserved. With increasing global awareness and demand for mental health solutions, this breakthrough presents a potential paradigm shift in treatment approaches. By identifying possible biological subtypes within disorders, BullFrog AI and LIBD are not only advancing scientific understanding but also opening doors to novel therapeutic pathways and personalized treatment strategies.

精神疾病新疗法的市场机会巨大且服务不足。随着全球对心理健康解决方案的认识和需求的提高,这一突破为治疗方法带来了潜在的模式转变。通过识别疾病中可能的生物亚型,BullFrog AI和LIBD不仅促进了科学理解,而且为新的治疗途径和个性化治疗策略打开了大门。

The agreement between the organizations, announced in September 2023, granted BullFrog AI exclusive access to LIBD's brain data, with the potential to commercialize products or services derived from the collaboration. The partnership represents a unique synergy between AI-driven analysis and world-class neuropsychiatric research, setting a new standard in the pursuit of effective treatments for brain disorders.

这些组织于2023年9月宣布的协议授予BullFrog AI独家访问LIBD大脑数据的权限,有可能将合作产生的产品或服务商业化。该合作伙伴关系代表了人工智能驱动的分析与世界一流的神经精神病学研究之间的独特协同作用,为寻求脑部疾病的有效治疗树立了新的标准。

About the Lieber Institute for Brain Development (LIBD)

关于利伯大脑发育研究所(LIBD)

The mission of the Lieber Institute for Brain Development and the Maltz Research Laboratories is to translate the understanding of basic genetic and molecular mechanisms of schizophrenia and related developmental brain disorders into clinical advances that change the lives of affected individuals. LIBD is an independent, not-for-profit 501(c)(3) organization and a Maryland tax-exempt medical research institute. The Lieber Institute's brain repository of more than 4,000 human brains is the largest collection of postmortem brains for the study of neuropsychiatric disorders in the world.

利伯大脑发育研究所和马尔茨研究实验室的使命是将对精神分裂症和相关发育性脑部疾病的基本遗传和分子机制的理解转化为改变患者生活的临床进展。LIBD是一个独立的非营利性501(c)(3)组织,也是马里兰州的一家免税医学研究机构。利伯研究所的大脑存储库拥有4,000多个人类大脑,是世界上用于神经精神疾病研究的最大验尸大脑库。

About BullFrog AI

BullFrog AI

BullFrog AI is a technology-enabled drug development company using Artificial Intelligence and machine learning to enable the successful development of pharmaceuticals and biologics. Through its collaborations with leading research institutions, BullFrog AI is at the forefront of AI-driven drug development using its proprietary bfLEAP artificial intelligence platform to create and analyze networks of biological, clinical, and real-world data spanning from early discovery to late-stage clinical trials. BullFrog AI is deploying bfLEAP for use at several critical stages of development with the intention of streamlining data analytics in therapeutics development, decreasing the overall development costs by decreasing failure rates for new therapeutics.

BullFrog AI 是一家以技术为导向的药物开发公司,使用人工智能和机器学习来实现药物和生物制剂的成功开发。通过与领先研究机构的合作,BullFrog AI处于人工智能驱动的药物开发的最前沿,使用其专有的bFleap人工智能平台来创建和分析从早期发现到后期临床试验的生物、临床和现实世界数据网络。BullFrog AI正在部署bFleap,用于开发的几个关键阶段,目的是简化疗法开发中的数据分析,通过降低新疗法的失败率来降低总体开发成本。

For more information visit BullFrog AI at:

欲了解更多信息,请访问 BullFrog AI,网址为:

Website:

网站:

LinkedIn:

领英:

Safe Harbor Statement

安全港声明

This press release contains forward-looking statements. We base these forward-looking statements on our expectations and projections about future events, which we derive from the information currently available to us. Such forward-looking statements relate to future events or our future performance, including: our financial performance and projections; our growth in revenue and earnings; and our business prospects and opportunities. You can identify forward-looking statements by those that are not historical in nature, particularly those that use terminology such as "may," "should," "expects," "anticipates," "contemplates," "estimates," "believes," "plans," "projected," "predicts," "potential," or "hopes" or the negative of these or similar terms. In evaluating these forward-looking statements, you should consider various factors, including: our ability to change the direction of the Company; our ability to keep pace with new technology and changing market needs; and the competitive environment of our business. These and other factors may cause our actual results to differ materially from any forward-looking statement. Forward-looking statements are only predictions. The forward-looking events discussed in this press release and other statements made from time to time by us or our representatives, may not occur, and actual events and results may differ materially and are subject to risks, uncertainties, and assumptions about us. We are not obligated to publicly update or revise any forward-looking statement, whether as a result of uncertainties and assumptions, the forward-looking events discussed in this press release and other statements made from time to time by us or our representatives might not occur.

本新闻稿包含前瞻性陈述。这些前瞻性陈述是基于我们对未来事件的预期和预测,这些预期和预测是我们从目前获得的信息中得出的。此类前瞻性陈述与未来事件或我们的未来业绩有关,包括:我们的财务业绩和预测;我们的收入和收益增长;以及我们的业务前景和机会。您可以通过非历史性质的前瞻性陈述来识别前瞻性陈述,尤其是那些使用诸如 “可能”、“应该”、“期望”、“预期”、“考虑”、“估计”、“相信”、“计划”、“预测”、“潜在” 或 “希望” 等术语或这些或类似术语的否定词的陈述。在评估这些前瞻性陈述时,您应考虑各种因素,包括:我们改变公司方向的能力;我们跟上新技术和不断变化的市场需求的能力;以及我们业务的竞争环境。这些因素和其他因素可能导致我们的实际业绩与任何前瞻性陈述存在重大差异。前瞻性陈述只是预测。本新闻稿中讨论的前瞻性事件以及我们或我们的代表不时发表的其他声明可能不会发生,实际事件和结果可能存在重大差异,并受风险、不确定性和对我们的假设的影响。我们没有义务公开更新或修改任何前瞻性陈述,无论是由于不确定性和假设,本新闻稿中讨论的前瞻性事件以及我们或我们的代表不时发表的其他声明都可能不会发生。

Contact:

联系人:

Investors
Dave Gentry
RedChip Companies, Inc.
BFRG@redchip.com
800-733-2447

投资者
戴夫·金特里
RedChip 公司有限公司
BFRG@redchip.com
800-733-2447

SOURCE: BullFrog AI Holdings, Inc.

资料来源:BullFrog 人工智能控股公司


声明:本内容仅用作提供资讯及教育之目的,不构成对任何特定投资或投资策略的推荐或认可。 更多信息
    抢沙发