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Kronos Bio To Present Data At ACR Convergence 2024 To Support P300 KAT Inhibition As An Approach To Anti-Inflammatory Therapy

Kronos Bio To Present Data At ACR Convergence 2024 To Support P300 KAT Inhibition As An Approach To Anti-Inflammatory Therapy

kronos bio将在2024年ACR会议上展示数据,以支持P300 KAt抑制作为一种抗炎疗法的方法
Benzinga ·  09/25 09:08

– Through selective inhibition of proinflammatory transcription, p300 KAT inhibition modulates the activity and function of multiple pro-inflammatory signaling pathways that drive chronic inflammatory diseases –

通过选择性抑制促炎症转录,p300 KAt抑制剂调节驱动慢性炎症性疾病的多个促炎发布信号通路的活性和功能

– Oral presentation taking place on Monday, November 18, 2024, from 4:15 p.m. to 4:30 p.m. EST –

口头报告将于2024年11月18日星期一下午4:15至4:30 EST举行

SAN MATEO, Calif. and CAMBRIDGE, Mass., Sept. 25, 2024 (GLOBE NEWSWIRE) -- Kronos Bio, Inc. (NASDAQ:KRON), a company dedicated to developing small molecule therapeutics that address cancers and other diseases driven by deregulated transcription, today announced that it will present preclinical data from its p300 KAT inhibitor program for autoimmune indications at the American College of Rheumatology's annual meeting, ACR Convergence 2024, being held from November 14 to 19, 2024 in Washington, DC.

加利福尼亚州圣马特奥和马萨诸塞州剑桥,2024年9月25日(环球新闻社)-- kronos bio公司(纳斯达克:KRON),一家致力于开发针对由失调转录驱动的癌症和其他疾病的小分子治疗药物的公司,今日宣布将于2024年11月14日至19日在华盛顿特区举行的美国风湿病学会年会ACR Convergence 2024上,展示其针对自身免疫疾病的p300 KAt抑制剂项目的临床前数据

Kronos Bio is exploring the utility of a p300 KAT inhibitor for autoimmune indications given the role of interferon regulatory factor 4 (IRF4) and p300 in B cells, T cells and other immune cells. The data being presented at the meeting support the role of p300 in inflammation, and the Company remains on track to announce a development candidate for autoimmune diseases by the end of 2024.

kronos bio正在探索利用p300 KAt抑制剂用于自身免疫疾病治疗的可行性,考虑到干扰素调节因子4(IRF4)和p300在b细胞和其他免疫细胞中的作用。会议上发布的数据支持p300在炎症中的作用,公司计划在2024年底之前宣布用于自身免疫疾病的开发候选药物

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