The following is a summary of the Lisata Therapeutics, Inc. (LSTA) Q3 2024 Earnings Call Transcript:

Financial Performance:

• Lisata Therapeutics reported a decrease in operating expenses for Q3 2024, totaling $5.3 million compared to $6 million in the same period last year.

• Research and development expenses decreased by 24.8%, largely due to reduced expenses in clinical research organization and lower equity expense associated with Phase IIa BOLSTER trial modifications.

• General and administrative expenses saw an increase of 8.1%, attributed to higher consulting expenses.

• Net losses improved to $4.9 million in Q3 2024 from $5.3 million in Q3 2023.

Business Progress:

• Lisata is advancing the development of certepetide across multiple solid tumors including pancreatic, cholangiocarcinoma, and others, with ongoing and planned clinical trials such as the ASCEND and BOLSTER trials.

• Significant regulatory designations have been achieved, including orphan drug and Fast Track designations, enhancing the development pathway for certepetide.

• The company has initiated preclinical investigations of certepetide for non-oncological uses, specifically in the treatment of endometriosis, indicating a strategic expansion of the therapeutic applications of certepetide.

Opportunities:

• Lisata continues to explore strategic partnerships and expand its development strategy in both oncologic and non-oncologic fields, leveraging existing clinical and preclinical collaborations to maximize the therapeutic potential of certepetide.

Risks:

• Slow initial enrollment rate in the GBM trial, particularly in Latvia, has posed challenges, despite optimization efforts. This might impact the timelines and expected outcomes of the trial.

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