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Tonix Pharmaceuticals Publishes Peer-Reviewed Publication In MSphere Journal Highlighting Tolerability Of Its Single-Dose Mpox And Smallpox Vaccine Candidate TNX-801, In Immune-Compromised Animals

Tonix Pharmaceuticals Publishes Peer-Reviewed Publication In MSphere Journal Highlighting Tolerability Of Its Single-Dose Mpox And Smallpox Vaccine Candidate TNX-801, In Immune-Compromised Animals

tonix pharmaceuticals发表了在《MSphere Journal》中发表的经同行评议的论文,重点介绍了其单剂量Mpox和天花疫苗候选药TNX-801在免疫受损动物中的耐受性。
Benzinga ·  11/13 09:07

The World Health Organization (WHO) declared the spread of new Clade Ib Mpox a public health emergency of international concern (PHEIC): Second Mpox-related WHO PHEIC declaration in two years

世界卫生组织(WHO)将新克莱德Ib Mpox的传播宣布为国际关注的公共卫生紧急事件(PHEIC):这是两年来第二次与Mpox相关的WHO PHEIC声明

Clade Ib Mpox cases detected in 16 African countries and outside of Africa, in Sweden, Thailand, Singapore, India, Germany and England

在16个非洲国家以及瑞典、泰国、新加坡、印度、德国和英国发现了克莱德Ib Mpox病例

Single-dose mpox vaccines with durable protection may be required to address global health emergency

可能需要单剂量的mpox疫苗以提供持久的保护,来应对全球健康紧急事件

TNX-801 was shown to be more than 10- to 1,000-fold more attenuated (or less virulent) compared to the older vaccinia smallpox vaccines: Tolerability of TNX‐801 vaccination in immune-compromised animal models supports clinical development

与旧的水痘疫苗相比,TNX-801的减毒超过了10到1,000倍(或致病性更低):TNX-801在免疫受损动物模型中的耐受性支持了其临床开发

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