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Humacyte Presents Preclinical Results Of Small-Diameter ATEV For Coronary Artery Bypass Grafting At American Heart Association's Scientific Sessions 2024; SdATEV Was Observed To Recellularize With Host Cells And Remodel To Effectively Reduce The...

Humacyte Presents Preclinical Results Of Small-Diameter ATEV For Coronary Artery Bypass Grafting At American Heart Association's Scientific Sessions 2024; SdATEV Was Observed To Recellularize With Host Cells And Remodel To Effectively Reduce The...

Humacyte在2024年美国心脏协会科学会议上展示了小直径ATEV用于冠状动脉旁路移植的临床前结果;观察到SdATEV与宿主细胞重建,并重塑以有效减少...
Benzinga ·  2024/11/18 08:02

Humacyte Presents Preclinical Results Of Small-Diameter ATEV For Coronary Artery Bypass Grafting At American Heart Association's Scientific Sessions 2024; SdATEV Was Observed To Recellularize With Host Cells And Remodel To Effectively Reduce The Initial Size Mismatch Between The SdATEV And The Animal's Native Artery

Humacyte在2024年美国心脏协会科学会议上展示了小直径无细胞组织工程血管(SdATEV)在冠状动脉旁路移植中的临床前结果;观察到SdATEV与宿主细胞重新细胞化并重塑,有效减少SdATEV与动物本身动脉之间的初始尺寸不匹配。

– sdATEVs maintained sustained patency throughout the six-month study –

– SdATEV在为期六个月的研究中保持持续通畅 –

– sdATEV was observed to recellularize with host cells and remodel to effectively reduce the initial size mismatch between the sdATEV and the animal's native artery –

– 观察到SdATEV与宿主细胞重新细胞化并重塑,有效减少SdATEV与动物本身动脉之间的初始尺寸不匹配 –

DURHAM, N.C., Nov. 18, 2024 (GLOBE NEWSWIRE) -- Humacyte, Inc. (NASDAQ:HUMA), a clinical-stage biotechnology platform company developing universally implantable, bioengineered human tissue at commercial scale, announced the presentation of positive preclinical results of the small-diameter (3.5mm) acellular tissue engineered vessel (sdATEV) in a non-human primate model of coronary artery bypass grafting (CABG). In the six-month preclinical CABG model the sdATEV was observed to sustain patency (blood flow), recellularized with the animals' host cells, and remodeled to effectively reduce the initial size mismatch between the sdATEV and the animals' native artery.

达勒姆,北卡罗来纳州,2024年11月18日(环球新闻通讯社) -- Humacyte公司(纳斯达克:HUMA),一家临床阶段的生物技术平台公司,正在开发可普遍植入的、生物工程的人体组织,并以商业规模进行宣布,在非人灵长类动物的冠状动脉旁路移植(CABG)模型中展示了小直径(3.5毫米)无细胞组织工程血管(SdATEV)的积极临床前结果。在为期六个月的临床前CABG模型中,观察到SdATEV维持通畅(血流),与动物的宿主细胞重新细胞化,并重塑,有效减少SdATEV与动物本身动脉之间的初始尺寸不匹配。

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