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Evaxion to Present Preclinical Proof-of-Concept for Precision ERV Cancer Vaccine Concept at ESMO Immuno-Oncology Congress

Evaxion to Present Preclinical Proof-of-Concept for Precision ERV Cancer Vaccine Concept at ESMO Immuno-Oncology Congress

Evaxion将在ESMO免疫肿瘤大会上展示精准ERV癌症生物-疫苗概念的临床前概念证明。
Evaxion Biotech ·  12/02 13:00

COPENHAGEN, Denmark, December 2, 2024 - Evaxion Biotech A/S (NASDAQ: EVAX) ("Evaxion"), a clinical-stage TechBio company specializing in developing AI-Immunology powered vaccines, will present preclinical Proof-of-Concept for its precision cancer vaccine concept, targeting non-conventional ERV (endogenous retrovirus) tumor antigens shared across patients at the ESMO Immuno-Oncology Congress, taking place from December 11-13, 2024, in Geneva, Switzerland.

丹麦哥本哈根,2024年12月2日——专门开发人工智能免疫疫苗的临床阶段TechBio公司Evaxion Biotech A/S(纳斯达克股票代码:EVAX)(“Evaxion”)将在2024年12月11日至13日举行的ESMO免疫肿瘤学大会上展示其精准癌症疫苗概念的临床前概念验证,该疫苗针对患者共享的非常规ERV(内源性逆转病毒)肿瘤抗原,在瑞士日内瓦。

The data to be presented stems from studies in human cells and mouse tumor models. The studies investigated human T-cell responses and mouse tumor growth inhibition induced by precision ERV vaccine targets identified using Evaxion's AI-Immunology platform.

将要提供的数据来自对人体细胞和小鼠肿瘤模型的研究。这些研究调查了由使用Evaxion的人工智能免疫学平台确定的精确ERV疫苗靶标引起的人类T细胞反应和小鼠肿瘤生长抑制作用。

AI-Immunology can select ERV antigens for precision therapeutic cancer vaccines, offering therapeutic options for multiple specific cancer types and potentially enabling treatment for patients who are unresponsive to conventional cancer immunotherapy.

人工智能免疫学可以为精准的治疗性癌症疫苗选择ERV抗原,为多种特定癌症类型提供治疗选择,并有可能为对传统癌症免疫疗法无反应的患者提供治疗。

The new concept of deploying ERVs as vaccine targets allows for designing precision cancer vaccines that could be effective across diverse immune system characteristics, making them suitable for a wide range of patients. Evaxion plans to utilize this now preclinically validated concept to design new precision vaccine candidates to complement our existing pipeline of personalized cancer vaccines.

部署ERV作为疫苗靶标的新概念允许设计精确的癌症疫苗,这些疫苗可以有效应对不同的免疫系统特征,使其适用于各种患者。Evaxion计划利用这一现已通过临床前验证的概念来设计新的精准候选疫苗,以补充我们现有的个性化癌症疫苗产品线。

Conference presentation details:

会议演示详情:

Abstract title: AI-designed cancer vaccines: antigens from the dark genome are promising cancer vaccine targets
Poster#: 124P
Location: Foyer Mezzanine
Date/Time: December 12, 2024, at 12.30 CET/06.30 EST
Presenter: Daniela Kleine-Kohlbrecher, Senior Project Manager at Evaxion
摘要标题: 人工智能设计的癌症疫苗:来自黑暗基因组的抗原是有希望的癌症疫苗靶标
海报 #: 124 页
地点: 门厅夹层
日期/时间: 2024 年 12 月 12 日,欧洲中部时间 12:30 /美国东部标准时间 06.30
演示者: Evaxion 高级项目经理 Daniela Kleine-Kohlbrecher


Contact information

Evaxion Biotech A/S
Mads Kronborg
Vice President, Investor Relations & Communication
+45 53 54 82 96
mak@evaxion-biotech.com


联系信息
Evaxion Biotech A/S
马兹·克伦博格
投资者关系与传播副总裁
+45 53 54 82 96
mak@evaxion-biotech.com

About EVAXION
Evaxion Biotech A/S is a pioneering TechBio company based upon its AI platform, AI-Immunology. Evaxion's proprietary and scalable AI prediction models harness the power of artificial intelligence to decode the human immune system and develop novel immunotherapies for cancer, bacterial diseases, and viral infections. Based upon AI-Immunology, Evaxion has developed a clinical-stage oncology pipeline of novel personalized vaccines and a preclinical infectious disease pipeline in bacterial and viral diseases with high unmet medical needs. Evaxion is committed to transforming patients' lives by providing innovative and targeted treatment options. For more information about Evaxion and its groundbreaking AI-Immunology platform and vaccine pipeline, please visit our website.

关于 EVAXION
Evaxion Biotech A/S是一家基于其人工智能平台AI免疫学的开创性TechBio公司。Evaxion 专有且可扩展的人工智能预测模型利用人工智能的力量来解码人体免疫系统,开发针对癌症、细菌性疾病和病毒感染的新型免疫疗法。基于人工智能免疫学,Evaxion开发了临床阶段的新型个性化疫苗的肿瘤学产品线,以及针对未满足大量医疗需求的细菌和病毒性疾病的临床前传染病管线。Evaxion致力于通过提供创新的有针对性的治疗方案来改变患者的生活。有关Evaxion及其开创性的人工智能免疫学平台和疫苗管道的更多信息,请访问我们的网站。

Forward-looking statement
This announcement contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The words "target," "believe," "expect," "hope," "aim," "intend," "may," "might," "anticipate," "contemplate," "continue," "estimate," "plan," "potential," "predict," "project," "will," "can have," "likely," "should," "would," "could," and other words and terms of similar meaning identify forward-looking statements. Actual results may differ materially from those indicated by such forward-looking statements as a result of various factors, including, but not limited to, risks related to: our financial condition and need for additional capital; our development work; cost and success of our product development activities and preclinical and clinical trials; commercializing any approved pharmaceutical product developed using our AI platform technology, including the rate and degree of market acceptance of our product candidates; our dependence on third parties including for conduct of clinical testing and product manufacture; our inability to enter into partnerships; government regulation; protection of our intellectual property rights; employee matters and managing growth; our ADSs and ordinary shares, the impact of international economic, political, legal, compliance, social and business factors, including inflation, and the effects on our business from other significant geo-political and macro-economic events; and other uncertainties affecting our business operations and financial condition. For a further discussion of these risks, please refer to the risk factors included in our most recent Annual Report on Form 20-F and other filings with the U.S. Securities and Exchange Commission (SEC), which are available at www.sec.gov. We do not assume any obligation to update any forward-looking statements except as required by law.

前瞻性陈述
本公告包含经修订的1933年《证券法》第27A条和经修订的1934年《证券交易法》第21E条所指的前瞻性陈述。“目标”、“相信”、“期望”、“希望”、“目标”、“打算”、“可能”、“预测”、“考虑”、“继续”、“估计”、“计划”、“潜力”、“预测”、“项目”、“将会”、“可能”、“可能”、“应该”、“会”、“可能” 等词语具有相似含义的术语用于识别前瞻性陈述。由于各种因素,实际结果可能与此类前瞻性陈述所示结果存在重大差异,包括但不限于以下方面的风险:我们的财务状况和对额外资本的需求;我们的开发工作;我们的产品开发活动以及临床前和临床试验的成本和成功;使用我们的人工智能平台技术开发的任何经批准的药品的商业化,包括候选产品的市场接受率和程度;我们对第三方的依赖,包括进行临床测试和产品制造;我们无法建立合作伙伴关系;政府监管;保护我们的知识产权;员工事务和增长管理;我们的ADS和普通股;包括通货膨胀在内的国际经济、政治、法律、合规、社会和商业因素的影响,以及其他重大地缘政治和宏观经济事件对我们业务的影响;以及影响我们业务运营和财务状况的其他不确定性。有关这些风险的进一步讨论,请参阅我们最新的20-F表年度报告和向美国证券交易委员会(SEC)提交的其他文件中包含的风险因素,这些文件可在www.sec.gov上查阅。除非法律要求,否则我们不承担任何更新任何前瞻性陈述的义务。

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