share_log

Amylyx and Gubra Join Forces for Peptide Drug Discovery Collaboration

Amylyx and Gubra Join Forces for Peptide Drug Discovery Collaboration

Amylyx和Gubra联合开展肽类药物发现合作
Benzinga ·  2024/12/30 06:34

Today, Gubra A/S ("Company"), a company specializing in pre-clinical contract research services and peptide-based drug discovery within metabolic and fibrotic diseases, announced a collaboration with Amylyx Pharmaceuticals, Inc. ("Amylyx") for the development of a potential novel long-acting GLP-1 receptor antagonist. "We are pleased to partner with Amylyx to advance GLP-1 receptor antagonism research. This collaboration and development agreement is an example of leading pharmaceutical companies partnering with us for our machine learning-based peptide drug discovery platform. This is yet another testimony that our streaMLine platform can be used to develop peptide drug candidates for a very broad range of diseases," said Henrik Blou, CEO of Gubra. This collaboration brings together Gubra's expertise in quickly screening and identifying potent peptide therapeutics and Amylyx' expertise in developing novel therapies for communities with high unmet needs. At the end of the screening period, Gubra and Amylyx anticipate identifying a lead development candidate to enter Investigational New Drug (IND)-enabling studies. Amylyx then has the option to lead development once the drug peptide therapeutic has been identified. Under the agreement, Gubra will receive upfront and research payments and may receive more than $50 million in success-based development and commercialization milestones plus mid single digit royalties on worldwide net sales

今天,Gubra A/S("公司")是一家专注于代谢和纤维化疾病的临床前合同研究服务以及基于肽的药物发现的公司,宣布与Amylyx Pharmaceuticals, Inc.("Amylyx")合作开发一种潜在的新型长效GLP-1受体拮抗剂。Gubra的首席执行官Henrik Blou表示:"我们很高兴与Amylyx合作,推动GLP-1受体拮抗剂的研究。这项合作和开发协议是领先药品公司与我们基于机器学习的肽药物发现平台合作的一个例证。这再次证明我们的streaMLine平台可以用于开发用于非常广泛疾病的肽药物候选。" 此次合作结合了Gubra在快速筛选和识别有效肽治疗方面的专业知识与Amylyx在为高未满足需求的社区开发新疗法方面的专业知识。在筛选期结束时,Gubra和Amylyx预计会识别出一个领先的开发候选,以进入临床研究(IND)启动研究。 一旦药物肽治疗被识别,Amylyx将有选择继续开发的权利。根据协议,Gubra将获得预付款和研究付款,并可能会获得超过5000万美元的基于成功的开发和商业化里程碑,此外还包括全球净销售额的中位数单数字的特许权使用费。

声明:本内容仅用作提供资讯及教育之目的,不构成对任何特定投资或投资策略的推荐或认可。 更多信息
    抢沙发