U.S. stocks traded lower this morning, with the $Dow Jones Industrial Average (.DJI.US)$ index falling more than 100 points on Tuesday.

Following the market opening Tuesday, the Dow traded down 0.28% to 37,584.41 while the $Nasdaq Composite Index (.IXIC.US)$ fell 1.35% to 14,808.88. The $S&P 500 Index (.SPX.US)$ also fell, dropping, 0.72% to 4,735.41.

Leading and Lagging Sectors

Energy shares rose by 1.1% on Tuesday.

In trading on Tuesday, information technology shares fell by 1.8%.

Top Headline

The S&P Global manufacturing PMI was revised lower to 47.9 in December versus a preliminary level of 48.2, and versus November's level of 49.4.

Equities Trading UP

$Longboard Pharmaceuticals (LBPH.US)$ shares shot up 198% to $17.95 after the company announced topline data from the PACIFIC Study evaluating bexicaserin in patients with Developmental and Epileptic Encephalopathies.

Shares of $Cue Health (HLTH.US)$ got a boost, surging 42% to $0.2301 after falling 42% on Friday.

$Soligenix (SNGX.US)$ shares were also up, gaining 36% to $1.0300.
Soligenix announced publication demonstrating complete protection against filovirus disease in nonhuman primate models of ebola and marburg viruses.

Equities Trading DOWN

$Anavex Life Sciences (AVXL.US)$shares dropped 32% to $6.31 after the company provided an update on Rett Syndrome program.

Shares of $LumiraDx (LMDX.US)$ were down 34% to $0.0428. LumiraDx agreed to sell its point-of-care technology platform to Roche.

$China SXT Pharmaceuticals (SXTC.US)$was down, falling 29% to $2.82 after gaining 92% on Friday.

Commodities

In commodity news, oil traded up 0.1% to $71.72 while gold traded up 0.3% at $2,078.40.

Silver traded up 0.5% to $24.205 on Tuesday while copper fell 0.6% to $3.8665.

Euro zone

European shares were mostly higher today. The eurozone's STOXX 600 fell 0.3%, London's FTSE 100 fell 0.4% while Spain's IBEX 35 Index rose 0.6% The German DAX fell 0.1% French CAC 40 fell 0.5% while Italy's FTSE MIB Index rose 0.3%.

Bank lending to households in the Eurozone increased by 0.5% year-over-year to EUR 6.87 trillion in November. The HCOB Eurozone manufacturing PMI rose to 44.4 in December, from the preliminary level of 44.2.

The S&P Global UK manufacturing PMI was revised lower to 46.2 in December from the preliminary estimate of 46.4, while German manufacturing PMI was revised higher to 43.3 in December versus a preliminary reading of 43.1. The HCOB France manufacturing PMI declined to 42.1 in December versus 42.9 a month ago.

Asia Pacific Markets

Asian markets closed lower on Tuesday, with Hong Kong's Hang Seng Index falling 1.52% and China's Shanghai Composite Index falling 0.43%. India's S&P BSE Sensex, meanwhile, fell 0.53%.

The official NBS non-manufacturing PMI for China rose to 50.4 in December from November's reading of 50.2, while manufacturing PMI fell to 49.0 in from 49.4. Singapore's GDP increased by 2.8% year-over-year in the fourth quarter versus a revised 1.0% increase in the third quarter. The Judo Bank Australia manufacturing PMI fell to 47.6 in December versus a preliminary reading of 47.8.

Economics

The S&P Global manufacturing PMI was revised lower to 47.9 in December versus a preliminary level of 48.2, and versus November's level of 49.4.