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Verve Therapeutics Announces Appointment of Nia Tatsis, Ph.D., and Jodie Morrison to Its Board of Directors

Verve Therapeutics Announces Appointment of Nia Tatsis, Ph.D., and Jodie Morrison to Its Board of Directors

動力治療公司宣佈任命Ph.D. Nia Tatsis和Jodie Morrison爲其董事會成員
Verve Therapeutics ·  06/28 00:00

BOSTON, June 28, 2024 (GLOBE NEWSWIRE) -- Verve Therapeutics, a clinical-stage biotechnology company pioneering a new approach to the care of cardiovascular disease with single-course gene editing medicines, today announced the appointment of Nia Tatsis, Ph.D., and Jodie Morrison to its board of directors. Dr. Tatsis currently serves as executive vice president, chief regulatory and quality officer, of Vertex Pharmaceuticals. Ms. Morrison currently serves as chief executive officer and director of Q32 Bio Inc.

2024年6月28日,波士頓(GLOBE NEWSWIRE)——Verve Therapeutics一家臨床生物技術公司,專注於以單療程基因編輯藥物爲治療心血管病的新方法,今天宣佈任命Nia Tatsis博士和Jodie Morrison爲董事。Tatsis博士目前擔任Vertex Pharmaceuticals的執行副總裁,首席監管和質量官。 Morrison女士目前擔任Q32 Bio Inc.的首席執行官和董事。

"We are thrilled to have Nia and Jodie join Verve's board of directors, lending their decades of impressive experience leading and advising pharmaceutical and biotech companies through critical stages in drug development, manufacturing, and commercialization," said Sekar Kathiresan, M.D., co-founder and chief executive officer of Verve Therapeutics. "We look forward to their valuable insights as we focus on pipeline execution with the continued advancement of the Heart-2 clinical trial of VERVE-102 targeting the PCSK9 gene, the clinical trial initiation of VERVE-201 targeting the ANGPTL3 gene, and continued progress on our earlier stage LPA program."

“我們很高興Nia和Jodie加入Verve的董事會,他們貢獻了幾十年的卓越經驗,在藥物研發,製造和商業化的重要階段,領導和諮詢製藥和生物技術公司,” Verve Therapeutics的聯合創始人,首席執行官Sekar Kathiresan博士表示。 “我們期待他們寶貴的見解,同時我們專注於推進VERVE-102靶向xx基因的Heart-2臨床試驗的流程,VERVE-201靶向xx基因的臨床試驗的啓動以及我們早期階段LPA項目的持續進展。”PCSK9 基因靶向論在未來的醫學治療中擁有極大的發展前景。ANGPTL3針對心血管疾病的單式基因編輯製藥品VERVE-201臨床試驗已經開始。

"I deeply admire Verve's mission to change the trajectory of how cardiovascular disease is treated around the world. Their goal of transforming the chronic care model to single-course gene editing medicines is an important step as we look to improve the lives of people with heart disease," said Dr. Tatsis. "I look forward to working closely with the Verve leadership team and the board as the company continues to further progress its PCSK9, ANGPTL3, and LPA programs."

“我非常欽佩Verve改變全世界對心血管疾病治療的軌跡的使命。他們通過轉變慢性治療模式爲單一基因編輯藥物邁出重要一步,這是我們尋求改善患有心臟病人的生活的重要一步,“Tatsis博士表示。“我期待着與Verve領導團隊和董事會密切合作,因爲公司繼續推進其PCSK9,ANGPTL3和LPA計劃。”

"The opportunity to address the millions of people around the world with cardiovascular disease with a one-time treatment represents a truly important mission. I am excited to partner with the Verve team as they continue these efforts," said Ms. Morrison. "Verve is well-positioned to become a distinguished leader in the cardiovascular space, supported by its impressive team and transformative science."

“有機會用一次治療治療全球成百上千萬的心血管病患者代表着一個非常重要的使命。我很高興能夠與Verve團隊合作,繼續這些努力,“Morrison女士表示。“Verve在心血管領域處於非常有利的地位,由其令人印象深刻的團隊和顛覆性的科學支持。”

Nia Tatsis, Ph.D., joined Vertex Pharmaceuticals in 2017 and serves as the company's executive vice president, chief regulatory and quality officer. Prior to joining Vertex, Dr. Tatsis held positions of increasing responsibility at pharmaceutical companies including Sanofi, Pfizer, and Wyeth. Most recently, she served as vice president, head of global regulatory affairs, of the Sanofi Genzyme Business Unit. Dr. Tatsis currently serves as a member of the leadership council of the International Institute of New England. Previously, she served as a staff scientist and research fellow in immunology and vaccine development at the Wistar Institute. Dr. Tatsis received her Ph.D. in cell and molecular biology from the University of Vermont and completed a postdoctoral research fellowship in immunology at Thomas Jefferson University. She holds a B.S. in biology from Temple University.

Nia Tatsis博士於2017年加入Vertex Pharmaceuticals,擔任公司的執行副總裁,首席監管和質量官。在加入Vertex之前,Tatsis博士在製藥公司擔任逐步增加的職責,包括Sanofi,Pfizer和Wyeth。最近,她擔任中外合資公司Sanofi Genzyme事業部全球監管事務負責人。Tatsis博士目前擔任國際新英格蘭學院領導層委員會的成員。此前,她曾在Wistar Institute擔任免疫學和疫苗開發的科學家和研究員。Tatsis博士在佛蒙特大學獲得細胞和分子生物學博士學位,並在Thomas Jefferson大學完成了免疫學博士後研究學習,她擁有Temple大學生物學學士學位。

Jodie Morrison, chief executive officer and director of Q32 Bio Inc., brings two decades of biopharmaceutical leadership experience across private and public biotechnology and pharmaceutical companies from start-up to commercial stage. Ms. Morrison was previously chief executive officer of Cadent Therapeutics until its sale to Novartis in 2021. Ms. Morrison also served as interim chief executive officer of Keryx Biopharmaceuticals, Inc. (executed its merger of equals with Akebia Therapeutics, Inc. in 2018), acting chief operating officer of Syntimmune, Inc. (acquired by Alexion Pharmaceuticals, Inc.), and president and chief executive officer of Tokai Pharmaceuticals, Inc., where she oversaw the company's successful initial public offering (IPO) in 2014. Ms. Morrison currently serves as an advisor to Atlas Venture, where she previously served as a venture partner, and as a member of the board at Rectify Pharma and of the board of managers at Life Science Cares. Ms. Morrison holds a B.A. in neuroscience from Mount Holyoke College.

Q32 Bio Inc.首席執行官和董事Jodie Morrison在私營和上市生物技術和製藥公司中擁有20年的生物製藥領導經驗,涵蓋從初創公司到商業階段。Morrison女士曾擔任Cadent Therapeutics的首席執行官,直到其在2021年被Novartis收購。Morrison女士還擔任Keryx Biopharmaceuticals公司的代總裁(該公司在2018年通過平等合併與Akebia Therapeutics公司合併),Syntimmune公司的代首席運營官(其被Alexion Pharmaceuticals公司收購),並擔任Tokai Pharmaceuticals公司的總裁兼首席執行官,指導該公司2014年成功進行了首次公開發行(IPO)。 Morrison女士目前擔任Atlas Venture的顧問(此前擔任風險合夥人)和Rectify Pharma董事會成員以及Life Science Cares董事會成員。Morrison女士擁有Mount Holyoke College神經科學學士學位。

About Verve Therapeutics
Verve Therapeutics, Inc. (Nasdaq: VERV) is a clinical-stage genetic medicines company pioneering a new approach to the care of cardiovascular disease, potentially transforming treatment from chronic management to single-course gene editing medicines. The company's lead programs – VERVE-101, VERVE-102, and VERVE-201 – target genes that have been extensively validated as targets for lowering low-density lipoprotein cholesterol (LDL-C), a root cause of atherosclerotic cardiovascular disease (ASCVD). VERVE-101 and VERVE-102 are designed to permanently turn off the PCSK9 gene in the liver and are being developed initially for heterozygous familial hypercholesterolemia (HeFH) and ultimately to treat patients with established ASCVD who continue to be impacted by high LDL-C levels. VERVE-201 is designed to permanently turn off the ANGPTL3 gene in the liver and is initially being developed for homozygous familial hypercholesterolemia (HoFH) and for refractory hypercholesterolemia where patients still have high LDL-C despite treatment with maximally-tolerated standard of care therapies. For more information, please visit www.VerveTx.com.

關於Verve Therapeutics Verve Therapeutics,Inc.(納斯達克代碼:VERV)是一家臨床階段的遺傳藥品公司,開創了一種新的心血管疾病護理方式,可能將治療從慢性管理轉變爲單次基因編輯藥品。公司的主要項目VERVE-101、VERVE-102和VERVE-201針對已被廣泛驗證爲低密度脂蛋白膽固醇(LDL-C)降低的靶點基因,這是動脈粥樣硬化性心血管疾病(ASCVD)的根本原因。VERVE-101和VERVE-102旨在永久關閉肝臟中的PCSK9基因,並首先開發用於雜合子家族性高膽固醇血癥(HeFH),最終用於治療繼續受高LDL-C水平影響的已確診ASCVD患者。VERVE-201旨在永久關閉一種受體基因,該基因的降解被認爲是促進冠狀動脈血管單位深度和體積增加的關鍵步驟,因此是一種可能的靶切點,因爲它可能降低心血管病發作的風險。
Verve Therapeutics, Inc. (納斯達克:VERV)是一家臨床階段的遺傳藥品公司,開創了一種新的心血管疾病護理方式,可能將治療從慢性管理轉變爲單次基因編輯藥品。公司的主要項目VERVE-101、VERVE-102和VERVE-201針對已被廣泛驗證爲低密度脂蛋白膽固醇(LDL-C)降低的靶點基因,這是動脈粥樣硬化性心血管疾病(ASCVD)的根本原因。 PCSK9 VERVE-101和VERVE-102旨在永久關閉肝臟中的PCSK9基因,並首先開發用於雜合子家族性高膽固醇血癥(HeFH),最終用於治療繼續受高LDL-C水平影響的已確診ASCVD患者。VERVE-201旨在永久關閉一種受體基因,該基因的降解被認爲是促進冠狀動脈血管單位深度和體積增加的關鍵步驟,因此是一種可能的靶切點,因爲它可能降低心血管病發作的風險。 ANGPTL3該基因位於肝臟,最初用於家族性高膽固醇血癥的同型時,並用於在最大耐受標準治療法治療後仍然存在高低密度脂蛋白膽固醇的難治性高膽固醇血癥的治療。欲了解更多信息,請訪問www.VerveTx.com.

Cautionary Note Regarding Forward Looking Statements
This press release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995 that involve substantial risks and uncertainties, including statements regarding the company's research and development plans, and the potential advantages and therapeutic potential of the company's programs. All statements, other than statements of historical facts, contained in this press release, including statements regarding the company's strategy, future operations, future financial position, prospects, plans and objectives of management, are forward-looking statements. The words "anticipate," "believe," "continue," "could," "estimate," "expect," "intend," "may," "plan," "potential," "predict," "project," "should," "target," "will," "would" and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements are based on management's current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in, or implied by, such forward-looking statements. These risks and uncertainties include, but are not limited to, risks associated with the company's limited operating history; the company's ability to timely submit and receive approvals of regulatory applications for its product candidates; advance its product candidates in clinical trials; initiate, enroll and complete its ongoing and future clinical trials on the timeline expected or at all; correctly estimate the potential patient population and/or market for the company's product candidates; replicate in clinical trials positive results found in preclinical studies and/or earlier-stage clinical trials of VERVE-101, VERVE-102, and VERVE-201; advance the development of its product candidates under the timelines it anticipates in current and future clinical trials; obtain, maintain or protect intellectual property rights related to its product candidates; manage expenses; and raise the substantial additional capital needed to achieve its business objectives. For a discussion of other risks and uncertainties, and other important factors, any of which could cause the company's actual results to differ from those contained in the forward-looking statements, see the "Risk Factors" section, as well as discussions of potential risks, uncertainties and other important factors, in the company's most recent filings with the Securities and Exchange Commission and in other filings that the company makes with the Securities and Exchange Commission in the future. In addition, the forward-looking statements included in this press release represent the company's views as of the date hereof and should not be relied upon as representing the company's views as of any date subsequent to the date hereof. The company anticipates that subsequent events and developments will cause the company's views to change. However, while the company may elect to update these forward-looking statements at some point in the future, the company specifically disclaims any obligation to do so.

關於前瞻性聲明的警告
本新聞稿包含根據1995年《私人證券訴訟改革法》所作出的“前瞻性聲明”,其中包含公司的研究和發展計劃以及公司計劃的程序的潛在優勢和治療潛力等相關信息。本新聞稿中除了歷史真實事實之外的所有陳述,包括關於公司策略、未來業務、未來財務狀況、遠景、現在和未來管理目標的言論,皆屬於前瞻性聲明。雖然不是所有前瞻性聲明都包含這些識別詞,但“預計”、“相信”、“繼續”、“可以”、“估計”、“期望”、“意圖”、“應該”、“目標”、“將”和類似表達意思的其他詞語都預示着前瞻性聲明,爲了識別前瞻性聲明,不能以這些詞語爲限。所有前瞻性陳述都基於管理層未來活動的預期,並且受到可能導致實際結果與此前瞻性聲明的設置或意涵相反的多項風險和不確定性的影響。任何前瞻性聲明都會謹慎引導,儘管不是所有前瞻性聲明都包含這些識別詞,但“預計”、“相信”、“繼續”、“可以”、“估計”、“期望”、“意圖”、“應該”、“目標”、“將”和類似表達意思的其他詞語都預示着前瞻性聲明。這些風險和不確定性包括但不限於公司有限的運營歷史,公司能否按時提交和收到其產品候選國家監管批准的能力,按時在臨床試驗中推進其產品候選,正確估計公司產品候選的潛在患者人群和市場,不能在臨床試驗中複製VERVE-101,VERVE-102和VERVE-201的預臨床研究和/或初期臨床試驗中的正面結果;按照其目前和將來臨床試驗預期的時間表推進其產品候選開發,獲得,維護或保護與其產品候選相關的知識產權;管理支出;以及籌集實現其業務目標所需的大量額外資本。有關其他風險和不確定性的討論以及可能導致公司的實際結果與前瞻性聲明中的結果不同的風險,未來的重點事件和發展,詳見“風險因素”部分,以及公司與證券交易委員會以及未來所做的其他聲明中的潛在風險,不確定性或其他重要因素的討論。此外,本新聞稿中所包含的前瞻性聲明表明公司對於此時此刻的看法,並且不應作爲今後日期公司對此的觀點。公司預計後續事件和事態的發展會導致公司的看法發生變化。但是,雖然公司未來可能決定更新這些前瞻性聲明,但公司明確聲明不承擔此前瞻性聲明更新的任何責任。

Investor Contact
Jen Robinson
Verve Therapeutics, Inc.
jrobinson@vervetx.com

投資者聯繫方式
詹·羅賓遜
Verve Therapeutics,Inc。
jrobinson@vervetx.com

Media Contact
Ashlea Kosikowski
1AB
ashlea@1abmedia.com

媒體聯繫人
阿什莉·科西科夫斯基
1AB
ashlea@1abmedia.com

声明:本內容僅用作提供資訊及教育之目的,不構成對任何特定投資或投資策略的推薦或認可。 更多信息
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