The following is a summary of the Cognition Therapeutics, Inc. (CGTX) Q1 2024 Earnings Call Transcript:

Financial Performance:

• As of June 30, 2024, Cognition Therapeutics has cash and cash equivalents of approximately $28.5 million.

• Total grant funds remaining from the NIA are $57.3 million.

• The company estimates sufficient cash to fund operations into the second quarter of 2025.

• Reported a net loss of $7 million or $0.18 per share for Q2 2024.

Business Progress:

• Advanced multiple Phase 2 clinical trials for CNS and retina degenerative conditions.

• SHINE trial results showed a 39% slowing of cognitive decline in placebo-comparison, providing strong proof-of-concept.

• Preparing longer and larger trials, including SHIMMER trial for dementia with Lewy bodies.

• Further studies include the START trial for early Alzheimer's and MAGNIFY for dry age-related macular degeneration.

• Continual dissemination of scientific findings through publications and presentations.

Opportunities:

• Looking forward to continuing dialogue with pharmaceutical companies interested in CNS drugs, particularly for Alzheimer's disease.

• Potential to become a part of the developing paradigm for dementia treatments.

Risks:

• The SHINE trial did not achieve statistical significance on the ADAS-Cog 11 scale, highlighting challenges in demonstrating substantial clinical efficacy needed for regulatory success.

• The 300-milligram dose of CT1812 in clinical trials experienced liver enzyme elevations, posing potential safety concerns.

More details: Cognition Therapeutics IR

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