The following is a summary of the Twist Bioscience Corporation (TWST) Q4 2024 Earnings Call Transcript:

Financial Performance:

• Twist Bioscience reported a record quarter with revenue reaching $84.7 million, marking a 27% year-over-year increase and 4% sequentially.

• Annual revenue for fiscal year 2024 rose to $330 million, a 28% increase from the previous year.

• Gross margin for Q4 was reported at 45.1%, surpassing guidance and showing significant improvement from the previous fiscal year's 36.6%.

• Cash, cash equivalents, and short-term investments ended at $276.4 million as of September 30, 2024.

Business Progress:

• Twist Bioscience has strengthened its product offering, particularly in its Express portfolio, which includes clonal genes, gene fragments, DNA preps, and IgG proteins.

• The company continues to expand its market share, particularly in the NGS tools portfolio which is seeing strong demand in rare disease and cancer diagnostics.

• The Biopharma services segment marked a revenue pickup, attributed to an increased order volume which is expected to convert to revenue in three to nine months.

• Strategic partnerships and collaborations with Illumina, Adicet Bio, and Element further bolster the company's industry position.

Opportunities:

• The ongoing expansion of the NGS and SynBio sectors coupled with increasing orders indicates a robust demand environment for Twist's innovative product lines.

• The development and integration of proprietary enzymes presents a new market opportunity, enhancing product competitiveness and opening up new customer segments.

Risks:

• The gradual growth expected from new product segments, such as the DNA storage technology which is still under development, indicates a potential lag before these technologies significantly contribute to revenue.

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