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Hepion Pharmaceutical's Lead Drug Shows Antifibrotic Effects In Animal Studies

Benzinga Real-time News ·  2021/03/23 10:10

Hepion Pharmaceuticals Inc (NASDAQ: HEPA) has announced positive results from an in vivo study of CRV431.

  • In this study, the mouse model was treated for eight weeks with oral dosing of CRV431, or two comparator drugs, obeticholic acid, and elafibranor.
  • Fibrosis was reduced by 47% with CRV431, 35% with obeticholic acid, and 37% with elafibranor, relative to vehicle controls.
  • The company says that the results highlight a relatively short course of CRV431 treatment that can exert beneficial effects at an advanced stage of liver disease.
  • Price Action: HEPA shares trading 0.89% higher at $2.12 in market hours on the last check Tuesday.
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