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Novel Therapeutic Solutions Are Needed as Autism Rates Increase

Novel Therapeutic Solutions Are Needed as Autism Rates Increase

随着自闭症发病率的增加,需要新的治疗解决方案
newsfile ·  2023/03/29 08:31

Vancouver, British Columbia--(Newsfile Corp. - March 29, 2023) - Nova Mentis Life Science Corp. (CSE: NOVA) (FSE: HN3Q) (OTCQB: NMLSF) ("NOVA" or the "Company"), a biotechnology company and global leader in first-in-class psilocybin-based therapeutics and complementary diagnostics for neuroinflammatory disorders is highlighting the importance of developing new therapeutic solutions for autism spectrum disorder (ASD) following a new study showing autism is on the rise among young children.

温哥华,不列颠哥伦比亚省-(Newsfile Corp.-2023年3月29日)-Nova Mentis生命科学公司(CSE:NOVA)(FSE:HN3Q)(OTCQB:NMLSF)(“Nova”或“公司”),在一项新的研究表明自闭症在幼儿中呈上升趋势后,一家生物技术公司和一流的基于裸盖菇素的疗法和神经炎性疾病的补充诊断方面的全球领导者强调了为自闭症谱系障碍(ASD)开发新的治疗方案的重要性。

The report from the Centers for Disease Control and Prevention (CDC) in the United States revealed that about 1 in 36 children was identified with ASD in 2020. This number is a marked increase from a prevalence of 1 in 44 children in 2018 and 1 in 150 children in 2000. Furthermore, for the first time, the percentage of Asian, Black and Hispanic children diagnosed was higher than among White children.

美国疾病控制和预防中心(CDC)的这份报告显示,2020年,大约每36名儿童中就有1名被确认患有自闭症。这一数字明显高于2018年每44名儿童中有1名儿童和2000年每150名儿童中有1名儿童的患病率。此外,亚裔、黑人和西班牙裔儿童的确诊比例首次高于白人儿童。

"Autism is the fastest growing developmental disability in the world. Sadly, many families are struggling to find therapeutic solutions that actually work and are searching for new options to help improve the cognitive and behavioural symptoms associated with the disorder," stated Dr. Marvin S. Hausman MD, Chairman of NOVA's Scientific Advisory Board. "We believe psilocybin therapy has the potential to be a significant advancement in ASD health care. Specifically, the combination of new therapies with current advancements in AI and machine learning creates a diagnostic and therapeutic environment that can result in a major transformation in medical research, drug discovery and public health outcomes."

诺瓦科学咨询委员会主席马文·S·豪斯曼博士说:“自闭症是世界上增长最快的发育性残疾。可悲的是,许多家庭正在努力寻找有效的治疗方案,并正在寻找新的选择,以帮助改善与这种疾病相关的认知和行为症状。”我们相信裸盖菇素疗法有可能成为ASD医疗保健的重大进步。具体地说,新疗法与当前人工智能和机器学习的进步相结合,创造了一个诊断和治疗环境,可以导致医学研究、药物发现和公共卫生结果的重大转变。

NOVA is the first company in the world to conduct a human trial testing the efficacy of psilocybin on adults diagnosed with fragile X syndrome (FXS), the leading genetic cause of ASD. In December 2022, the Company was given the go-ahead from Health Canada to proceed with the first-ever Phase IIA clinical trial assessing repetitive, oral microdose psilocybin therapy for FXS. The Company intends to validate behavioural testing with state-of-the-art diagnostic and therapeutic biomarker technology, and machine learning artificial intelligence (AI).

Nova是世界上第一家对患有脆性X综合征(FXS)的成年人进行人体试验测试裸盖菇素疗效的公司,FXS是ASD的主要遗传原因。2022年12月,该公司获得加拿大卫生部的许可,开始进行有史以来第一个IIA期临床试验,评估重复的口服微剂量裸盖菇素治疗FXS。该公司打算利用最先进的诊断和治疗生物标记物技术以及机器学习人工智能(AI)来验证行为测试。

NOVA has completed production of pharmaceutical grade cGMP synthetic psilocybin 1.5 mg microdose capsules that will be used to advance the research and development steps needed for successful drug regulatory approval and future commercialization.

Nova公司已经完成了药用级cGMP合成裸盖菇素1.5 mg微剂量胶囊的生产,这些胶囊将用于推进成功获得药品监管批准和未来商业化所需的研究和开发步骤。

NOVA's preclinical research results, which were published in an international science journal, showed that a low microdose formulation of the Company's psilocybin drug significantly modulated behavioural and cognitive defects in a genetic model of FXS.

发表在一家国际科学期刊上的Nova公司的临床前研究结果表明,该公司的裸盖菇素药物的低微剂量配方显著调节了FXS遗传模型中的行为和认知缺陷。

RSU Grant

RSU Grant

Further, the Company has granted 500,000 restricted share units (the "RSUs") to a consultant of the Company. The RSUs are valid for a two-year term and are governed by the Company's RSU Plan, approved by the Company's shareholders on December 22, 2020. The RSUs are subject to a statutory hold period of four months and one day from the date of issuance.

此外,本公司已向本公司的一名顾问授予500,000股限制性股份单位(“股份单位”)。RSU的有效期为两年,受公司股东于2020年12月22日批准的公司RSU计划的管辖。回购股的法定持有期为4个月零1天,自发行之日起计。

Marketing Agreement

营销协议

The Company has engaged Octagon Media Corp., doing business as Wall Street Reporter ("WSR"), whereby WSR shall provide marketing services for a period of four (4) months commencing on March 27, 2023, in consideration of 1,400,000 common shares in the capital of the Company (the "Shares") at a deemed price of approximately $0.057 per Share. The Shares are subject to a statutory hold period of four months and one day from the date of issuance.

本公司已聘请八角形传媒公司,以华尔街记者的身分经营业务,据此,华尔街记者将于2023年3月27日起提供为期四(4)个月的营销服务,代价为公司股本中的1,400,000股普通股(“股份”),每股作价约0.057美元。该等股份的法定持有期为自发行日期起计四个月零一天。

About Nova Mentis Life Science Corp.

关于Nova Mentis生命科学公司

Nova Mentis Life Science Corp. is a Canadian-based biotechnology company and global leader in developing diagnostics and psilocybin-based therapeutics for neuroinflammatory disorders. Nova is the first biotech company to achieve orphan drug designation in both the United States and European Union for the use of psilocybin in the treatment of fragile X syndrome (FXS).

Nova Mentis生命科学公司是一家总部位于加拿大的生物技术公司,在开发神经炎性疾病的诊断和基于裸盖菇素的疗法方面处于全球领先地位。Nova是第一家在美国和欧盟获得使用裸盖菇素治疗脆性X综合征(FXS)的孤儿药物指定的生物技术公司。

NOVA's goal is to diagnose and treat debilitating chronic conditions that have unmet medical needs, such as autism spectrum disorder (ASD) and FXS.

Nova的目标是诊断和治疗尚未满足医疗需求的令人衰弱的慢性疾病,如自闭症谱系障碍(ASD)和FXS。

For further information on the Company, please visit or email info@novamentis.ca.

欲了解更多有关公司的信息,请访问或发送电子邮件至info@novamentis.ca。

On Behalf of the Board

我谨代表董事会

Will Rascan, President & CEO
Nova Mentis Life Science Corp.

威尔·拉斯坎,总裁兼首席执行官
Nova Mentis生命科学公司

Phone: 778-819-0244
Toll Free: 1-833-542-5323

电话:778-819-0244
免费电话:1-833-542-5323

Twitter: @novamentislsc
Instagram: @novamentislsc
Facebook: @novamentislsc

推特:@novamentislsc
Instagram:@novamentislsc
脸书:@novamentislsc

Neither the Canadian Securities Exchange nor its Market Regulator (as that term is defined in the policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release.

加拿大证券交易所及其市场监管机构(该术语在加拿大证券交易所的政策中定义)均不对本新闻稿的充分性或准确性承担责任。

This news release contains statements that constitute "forward-looking statements." Such forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause Nova Mentis Life Science's actual results, performance or achievements, or developments in the industry to differ materially from the anticipated results, performance or achievements expressed or implied by such forward-looking statements. Forward-looking statements are statements that are not historical facts and are generally, but not always, identified by the words "expects," "plans," "anticipates," "believes," "intends," "estimates," "projects," "potential" and similar expressions, or that events or conditions "will," "would," "may," "could" or "should" occur.

本新闻稿包含构成“前瞻性陈述”的陈述。此类前瞻性表述涉及已知和未知的风险、不确定性和其他因素,可能导致Nova Mentis生命科学公司的实际结果、业绩或成就或行业发展与此类前瞻性表述明示或暗示的预期结果、业绩或成就大不相同。前瞻性陈述是指不是历史事实的陈述,通常但并非总是由“预期”、“计划”、“预期”、“相信”、“打算”、“估计”、“项目”、“潜在”和类似的表述,或事件或条件“将”、“将”、“可能”、“可能”或“应该”发生。

To view the source version of this press release, please visit

要查看本新闻稿的源版本,请访问

声明:本内容仅用作提供资讯及教育之目的,不构成对任何特定投资或投资策略的推荐或认可。 更多信息
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