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疗效结果显示，本试验在第16周达到了共同主要终点。CM310组治疗16周时，达到EASI-75的受试者比例为66.9%，达到IGA评分为0或1分(IGA 0/1，即皮损完全清除或基本清除)且较基线下降≥2分的受试者比例为44.2%，均优于安慰剂组(分别为25.8%及16.1%)，两者均具备显著统计学差异(P<0.0001)。从基线至第16周瘙痒控制和生活质量方面均有显著改善，即CM310组治疗16周时，达到每日峰值瘙痒数字评估量表(PP-NRS)较基线改善≥4分的受试者百分比为35.9%，皮肤病生活质量指数(DLQI)较基线改善8.7分，均优于安慰剂组(11.7%和4.4分)，且均具备显著的统计学差异(P<0.0001)。安全方面，本试验安全性特征良好，CM310组治疗期不良事件(TEAE)的发生率与安慰剂组相当，大多数TEAE严重程度均为轻中度。