The following is a summary of the Panbela Therapeutics, Inc. (PBLA) Q1 2024 Earnings Call Transcript:

Financial Performance:

• Panbela reported Q1 2024 general and administrative expenses of approximately $1.2 million, a decrease from $1.4 million in Q1 2023.

• Research and development expenses increased to approximately $5.5 million in Q1 2024, up from $3.5 million in Q1 2023.

• Net loss for the quarter was $7.1 million, or $2.28 per diluted share, an increase from a net loss of $5.1 million, or $392.76 per diluted share, in Q1 2023.

• As of March 31, 2024, Panbela had a total cash amount of approximately $260,000, including approximately $8.1 million in net profits from their public offering which closed in January.

Business Progress:

• Panbela reported approximately half enrollment for the ASPIRE trial, with full enrollment expected by Q1 2025.

• Interim analysis for ASPIRE trial is projected for as early as Q1 2025.

• Progress has been made in several studies, including a Phase II study of eflornithine in type 1 diabetes, a Phase II study of ivospemin in platinum-resistant ovarian cancer, and a Phase I/II collaboration with Moffitt Cancer Center.

• A poster was presented by Panbela at the AACR annual meeting about ivospemin's efficacy.

• Panbela generated revenue from an asset sale to US WorldMeds, which included an upfront payment of $400,000 and an additional $775,000.

• New patents were obtained for a fixed dose combination of eflornithine and sulindac in the US and Canada.

More details: Panbela Therapeutics IR

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