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Verve Therapeutics Announces Appointment of Nia Tatsis, Ph.D., and Jodie Morrison to Its Board of Directors

Verve Therapeutics Announces Appointment of Nia Tatsis, Ph.D., and Jodie Morrison to Its Board of Directors

动力治疗公司宣布任命Ph.D. Nia Tatsis和Jodie Morrison为其董事会成员
Verve Therapeutics ·  06/28 00:00

BOSTON, June 28, 2024 (GLOBE NEWSWIRE) -- Verve Therapeutics, a clinical-stage biotechnology company pioneering a new approach to the care of cardiovascular disease with single-course gene editing medicines, today announced the appointment of Nia Tatsis, Ph.D., and Jodie Morrison to its board of directors. Dr. Tatsis currently serves as executive vice president, chief regulatory and quality officer, of Vertex Pharmaceuticals. Ms. Morrison currently serves as chief executive officer and director of Q32 Bio Inc.

2024年6月28日,波士顿(GLOBE NEWSWIRE)——Verve Therapeutics一家临床生物技术公司,专注于以单疗程基因编辑药物为治疗心血管病的新方法,今天宣布任命Nia Tatsis博士和Jodie Morrison为董事。Tatsis博士目前担任Vertex Pharmaceuticals的执行副总裁,首席监管和质量官。 Morrison女士目前担任Q32 Bio Inc.的首席执行官和董事。

"We are thrilled to have Nia and Jodie join Verve's board of directors, lending their decades of impressive experience leading and advising pharmaceutical and biotech companies through critical stages in drug development, manufacturing, and commercialization," said Sekar Kathiresan, M.D., co-founder and chief executive officer of Verve Therapeutics. "We look forward to their valuable insights as we focus on pipeline execution with the continued advancement of the Heart-2 clinical trial of VERVE-102 targeting the PCSK9 gene, the clinical trial initiation of VERVE-201 targeting the ANGPTL3 gene, and continued progress on our earlier stage LPA program."

“我们很高兴Nia和Jodie加入Verve的董事会,他们贡献了几十年的卓越经验,在药物研发,制造和商业化的重要阶段,领导和咨询制药和生物技术公司,” Verve Therapeutics的联合创始人,首席执行官Sekar Kathiresan博士表示。 “我们期待他们宝贵的见解,同时我们专注于推进VERVE-102靶向xx基因的Heart-2临床试验的流程,VERVE-201靶向xx基因的临床试验的启动以及我们早期阶段LPA项目的持续进展。”PCSK9 基因靶向论在未来的医学治疗中拥有极大的发展前景。ANGPTL3针对心血管疾病的单式基因编辑制药品VERVE-201临床试验已经开始。

"I deeply admire Verve's mission to change the trajectory of how cardiovascular disease is treated around the world. Their goal of transforming the chronic care model to single-course gene editing medicines is an important step as we look to improve the lives of people with heart disease," said Dr. Tatsis. "I look forward to working closely with the Verve leadership team and the board as the company continues to further progress its PCSK9, ANGPTL3, and LPA programs."

“我非常钦佩Verve改变全世界对心血管疾病治疗的轨迹的使命。他们通过转变慢性治疗模式为单一基因编辑药物迈出重要一步,这是我们寻求改善患有心脏病人的生活的重要一步,“Tatsis博士表示。“我期待着与Verve领导团队和董事会密切合作,因为公司继续推进其PCSK9,ANGPTL3和LPA计划。”

"The opportunity to address the millions of people around the world with cardiovascular disease with a one-time treatment represents a truly important mission. I am excited to partner with the Verve team as they continue these efforts," said Ms. Morrison. "Verve is well-positioned to become a distinguished leader in the cardiovascular space, supported by its impressive team and transformative science."

“有机会用一次治疗治疗全球成百上千万的心血管病患者代表着一个非常重要的使命。我很高兴能够与Verve团队合作,继续这些努力,“Morrison女士表示。“Verve在心血管领域处于非常有利的地位,由其令人印象深刻的团队和颠覆性的科学支持。”

Nia Tatsis, Ph.D., joined Vertex Pharmaceuticals in 2017 and serves as the company's executive vice president, chief regulatory and quality officer. Prior to joining Vertex, Dr. Tatsis held positions of increasing responsibility at pharmaceutical companies including Sanofi, Pfizer, and Wyeth. Most recently, she served as vice president, head of global regulatory affairs, of the Sanofi Genzyme Business Unit. Dr. Tatsis currently serves as a member of the leadership council of the International Institute of New England. Previously, she served as a staff scientist and research fellow in immunology and vaccine development at the Wistar Institute. Dr. Tatsis received her Ph.D. in cell and molecular biology from the University of Vermont and completed a postdoctoral research fellowship in immunology at Thomas Jefferson University. She holds a B.S. in biology from Temple University.

Nia Tatsis博士于2017年加入Vertex Pharmaceuticals,担任公司的执行副总裁,首席监管和质量官。在加入Vertex之前,Tatsis博士在制药公司担任逐步增加的职责,包括Sanofi,Pfizer和Wyeth。最近,她担任中外合资公司Sanofi Genzyme事业部全球监管事务负责人。Tatsis博士目前担任国际新英格兰学院领导层委员会的成员。此前,她曾在Wistar Institute担任免疫学和疫苗开发的科学家和研究员。Tatsis博士在佛蒙特大学获得细胞和分子生物学博士学位,并在Thomas Jefferson大学完成了免疫学博士后研究学习,她拥有Temple大学生物学学士学位。

Jodie Morrison, chief executive officer and director of Q32 Bio Inc., brings two decades of biopharmaceutical leadership experience across private and public biotechnology and pharmaceutical companies from start-up to commercial stage. Ms. Morrison was previously chief executive officer of Cadent Therapeutics until its sale to Novartis in 2021. Ms. Morrison also served as interim chief executive officer of Keryx Biopharmaceuticals, Inc. (executed its merger of equals with Akebia Therapeutics, Inc. in 2018), acting chief operating officer of Syntimmune, Inc. (acquired by Alexion Pharmaceuticals, Inc.), and president and chief executive officer of Tokai Pharmaceuticals, Inc., where she oversaw the company's successful initial public offering (IPO) in 2014. Ms. Morrison currently serves as an advisor to Atlas Venture, where she previously served as a venture partner, and as a member of the board at Rectify Pharma and of the board of managers at Life Science Cares. Ms. Morrison holds a B.A. in neuroscience from Mount Holyoke College.

Q32 Bio Inc.首席执行官和董事Jodie Morrison在私营和上市生物技术和制药公司中拥有20年的生物制药领导经验,涵盖从初创公司到商业阶段。Morrison女士曾担任Cadent Therapeutics的首席执行官,直到其在2021年被Novartis收购。Morrison女士还担任Keryx Biopharmaceuticals公司的代总裁(该公司在2018年通过平等合并与Akebia Therapeutics公司合并),Syntimmune公司的代首席运营官(其被Alexion Pharmaceuticals公司收购),并担任Tokai Pharmaceuticals公司的总裁兼首席执行官,指导该公司2014年成功进行了首次公开发行(IPO)。 Morrison女士目前担任Atlas Venture的顾问(此前担任风险合伙人)和Rectify Pharma董事会成员以及Life Science Cares董事会成员。Morrison女士拥有Mount Holyoke College神经科学学士学位。

About Verve Therapeutics
Verve Therapeutics, Inc. (Nasdaq: VERV) is a clinical-stage genetic medicines company pioneering a new approach to the care of cardiovascular disease, potentially transforming treatment from chronic management to single-course gene editing medicines. The company's lead programs – VERVE-101, VERVE-102, and VERVE-201 – target genes that have been extensively validated as targets for lowering low-density lipoprotein cholesterol (LDL-C), a root cause of atherosclerotic cardiovascular disease (ASCVD). VERVE-101 and VERVE-102 are designed to permanently turn off the PCSK9 gene in the liver and are being developed initially for heterozygous familial hypercholesterolemia (HeFH) and ultimately to treat patients with established ASCVD who continue to be impacted by high LDL-C levels. VERVE-201 is designed to permanently turn off the ANGPTL3 gene in the liver and is initially being developed for homozygous familial hypercholesterolemia (HoFH) and for refractory hypercholesterolemia where patients still have high LDL-C despite treatment with maximally-tolerated standard of care therapies. For more information, please visit www.VerveTx.com.

关于Verve Therapeutics Verve Therapeutics,Inc.(纳斯达克代码:VERV)是一家临床阶段的遗传药品公司,开创了一种新的心血管疾病护理方式,可能将治疗从慢性管理转变为单次基因编辑药品。公司的主要项目VERVE-101、VERVE-102和VERVE-201针对已被广泛验证为低密度脂蛋白胆固醇(LDL-C)降低的靶点基因,这是动脉粥样硬化性心血管疾病(ASCVD)的根本原因。VERVE-101和VERVE-102旨在永久关闭肝脏中的PCSK9基因,并首先开发用于杂合子家族性高胆固醇血症(HeFH),最终用于治疗继续受高LDL-C水平影响的已确诊ASCVD患者。VERVE-201旨在永久关闭一种受体基因,该基因的降解被认为是促进冠状动脉血管单位深度和体积增加的关键步骤,因此是一种可能的靶切点,因为它可能降低心血管病发作的风险。
Verve Therapeutics, Inc. (纳斯达克:VERV)是一家临床阶段的遗传药品公司,开创了一种新的心血管疾病护理方式,可能将治疗从慢性管理转变为单次基因编辑药品。公司的主要项目VERVE-101、VERVE-102和VERVE-201针对已被广泛验证为低密度脂蛋白胆固醇(LDL-C)降低的靶点基因,这是动脉粥样硬化性心血管疾病(ASCVD)的根本原因。 PCSK9 VERVE-101和VERVE-102旨在永久关闭肝脏中的PCSK9基因,并首先开发用于杂合子家族性高胆固醇血症(HeFH),最终用于治疗继续受高LDL-C水平影响的已确诊ASCVD患者。VERVE-201旨在永久关闭一种受体基因,该基因的降解被认为是促进冠状动脉血管单位深度和体积增加的关键步骤,因此是一种可能的靶切点,因为它可能降低心血管病发作的风险。 ANGPTL3该基因位于肝脏,最初用于家族性高胆固醇血症的同型时,并用于在最大耐受标准治疗法治疗后仍然存在高低密度脂蛋白胆固醇的难治性高胆固醇血症的治疗。欲了解更多信息,请访问www.VerveTx.com.

Cautionary Note Regarding Forward Looking Statements
This press release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995 that involve substantial risks and uncertainties, including statements regarding the company's research and development plans, and the potential advantages and therapeutic potential of the company's programs. All statements, other than statements of historical facts, contained in this press release, including statements regarding the company's strategy, future operations, future financial position, prospects, plans and objectives of management, are forward-looking statements. The words "anticipate," "believe," "continue," "could," "estimate," "expect," "intend," "may," "plan," "potential," "predict," "project," "should," "target," "will," "would" and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements are based on management's current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in, or implied by, such forward-looking statements. These risks and uncertainties include, but are not limited to, risks associated with the company's limited operating history; the company's ability to timely submit and receive approvals of regulatory applications for its product candidates; advance its product candidates in clinical trials; initiate, enroll and complete its ongoing and future clinical trials on the timeline expected or at all; correctly estimate the potential patient population and/or market for the company's product candidates; replicate in clinical trials positive results found in preclinical studies and/or earlier-stage clinical trials of VERVE-101, VERVE-102, and VERVE-201; advance the development of its product candidates under the timelines it anticipates in current and future clinical trials; obtain, maintain or protect intellectual property rights related to its product candidates; manage expenses; and raise the substantial additional capital needed to achieve its business objectives. For a discussion of other risks and uncertainties, and other important factors, any of which could cause the company's actual results to differ from those contained in the forward-looking statements, see the "Risk Factors" section, as well as discussions of potential risks, uncertainties and other important factors, in the company's most recent filings with the Securities and Exchange Commission and in other filings that the company makes with the Securities and Exchange Commission in the future. In addition, the forward-looking statements included in this press release represent the company's views as of the date hereof and should not be relied upon as representing the company's views as of any date subsequent to the date hereof. The company anticipates that subsequent events and developments will cause the company's views to change. However, while the company may elect to update these forward-looking statements at some point in the future, the company specifically disclaims any obligation to do so.

关于前瞻性声明的警告
本新闻稿包含根据1995年《私人证券诉讼改革法》所作出的“前瞻性声明”,其中包含公司的研究和发展计划以及公司计划的程序的潜在优势和治疗潜力等相关信息。本新闻稿中除了历史真实事实之外的所有陈述,包括关于公司策略、未来业务、未来财务状况、远景、现在和未来管理目标的言论,皆属于前瞻性声明。虽然不是所有前瞻性声明都包含这些识别词,但“预计”、“相信”、“继续”、“可以”、“估计”、“期望”、“意图”、“应该”、“目标”、“将”和类似表达意思的其他词语都预示着前瞻性声明,为了识别前瞻性声明,不能以这些词语为限。所有前瞻性陈述都基于管理层未来活动的预期,并且受到可能导致实际结果与此前瞻性声明的设置或意涵相反的多项风险和不确定性的影响。任何前瞻性声明都会谨慎引导,尽管不是所有前瞻性声明都包含这些识别词,但“预计”、“相信”、“继续”、“可以”、“估计”、“期望”、“意图”、“应该”、“目标”、“将”和类似表达意思的其他词语都预示着前瞻性声明。这些风险和不确定性包括但不限于公司有限的运营历史,公司能否按时提交和收到其产品候选国家监管批准的能力,按时在临床试验中推进其产品候选,正确估计公司产品候选的潜在患者人群和市场,不能在临床试验中复制VERVE-101,VERVE-102和VERVE-201的预临床研究和/或初期临床试验中的正面结果;按照其目前和将来临床试验预期的时间表推进其产品候选开发,获得,维护或保护与其产品候选相关的知识产权;管理支出;以及筹集实现其业务目标所需的大量额外资本。有关其他风险和不确定性的讨论以及可能导致公司的实际结果与前瞻性声明中的结果不同的风险,未来的重点事件和发展,详见“风险因素”部分,以及公司与证券交易委员会以及未来所做的其他声明中的潜在风险,不确定性或其他重要因素的讨论。此外,本新闻稿中所包含的前瞻性声明表明公司对于此时此刻的看法,并且不应作为今后日期公司对此的观点。公司预计后续事件和事态的发展会导致公司的看法发生变化。但是,虽然公司未来可能决定更新这些前瞻性声明,但公司明确声明不承担此前瞻性声明更新的任何责任。

Investor Contact
Jen Robinson
Verve Therapeutics, Inc.
jrobinson@vervetx.com

投资者联系方式
詹·罗宾逊
Verve Therapeutics,Inc。
jrobinson@vervetx.com

Media Contact
Ashlea Kosikowski
1AB
ashlea@1abmedia.com

媒体联系人
阿什莉·科西科夫斯基
1AB
ashlea@1abmedia.com

声明:本内容仅用作提供资讯及教育之目的,不构成对任何特定投资或投资策略的推荐或认可。 更多信息
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