NUCDF and Zevra Therapeutics Launch Check Ammonia Campaign To Highlight Critical Importance Of Prompt, Accurate Blood Ammonia Testing For Diagnosing Urea Cycle Disorders
NUCDF and Zevra Therapeutics Launch Check Ammonia Campaign To Highlight Critical Importance Of Prompt, Accurate Blood Ammonia Testing For Diagnosing Urea Cycle Disorders
Newborns with severe UCDs typically become catastrophically ill within 36-48 hours after birth. It is estimated that up to 20% of sudden infant death syndrome (SIDS) cases may be attributed to an undiagnosed inborn error of metabolism such as a UCD. Adults with undiagnosed UCDs may present at emergency rooms with staggering, confusion, combativeness and disorientation that is mistaken for alcohol or drug intoxication, and many die.The National Urea Cycle Disorders Foundation (NUCDF) and Zevra Therapeutics, Inc. (NASDAQ:ZVRA) are teaming up to launch an awareness campaign during the month of October to improve the diagnosis of urea cycle disorders (UCDs). Their goal is to highlight the critical importance of promptly checking blood ammonia levels and using proper testing techniques.
国家尿素循环紊乱基金会（NUCDF）和Zevra Therapeutics, Inc.（纳斯达克：ZVRA）正在合作，在十月份发起一场宣传活动，以改善尿素循环紊乱（UCDs）的诊断。他们的目标是突出及时检查血氨水平和使用正确测试技术的重要性。
A blood ammonia test is essential to uncover elevated ammonia levels (hyperammonemia), the classic sign of a urea cycle disorder. Resources on recognizing and testing for hyperammonemia are featured on the campaign website, checkammonia.com.
血氨试验对发现升高的氨水平（高氨血症），是尿素循环紊乱的经典症状至关重要。关于识别和测试高氨血症的资源已在活动网站checkammonia.com上展示。
Quickly diagnosing UCDs is critical. Toxic ammonia levels can rise rapidly in affected individuals, which if left untreated, can cause coma and death.
快速诊断UCDs至关重要。受影响个体中有毒氨水平可能迅速升高，若不及时治疗，可导致昏迷和死亡。
Newborns with severe UCDs typically become catastrophically ill within 36-48 hours after birth. It is estimated that up to 20% of sudden infant death syndrome (SIDS) cases may be attributed to an undiagnosed inborn error of metabolism such as a UCD. Adults with undiagnosed UCDs may present at emergency rooms with staggering, confusion, combativeness and disorientation that is mistaken for alcohol or drug intoxication, and many die.
新生儿患严重UCDs通常在出生后36-48小时内表现出灾难性病态。据估计，多达20%的猝死综合征（SIDS）病例可能归因于未诊断的先天代谢错误，如UCD。未被诊断的UCDs患者可能在急诊室表现出晕眩、混乱、好斗和迷失方向，被误认为醉酒或药物中毒，许多人因此死亡。
The campaign's primary message is that a blood ammonia test, performed promptly and properly, can save lives. Downloadable campaign resources focus on (1) Recognizing the signs of UCDs and promptly ordering a test and (2) Following proper test procedures.
该活动的主要信息是，及时、正确执行血氨测试可以挽救生命。可下载的活动资源重点关注（1）识别UCDs的迹象并及时下单测试和（2）遵循正确的测试程序。
