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Protagonist Therapeutics to Host Conference Call to Announce an Oral Peptide IL-17 Antagonist Development Candidate

Protagonist Therapeutics to Host Conference Call to Announce an Oral Peptide IL-17 Antagonist Development Candidate

Protagonist therapeutics 将召开电话会议,宣布一种口服肽IL-17拮抗剂开发候选药物
Accesswire ·  11/19 07:30

Webcast and conference call to be held be on Thursday, November 21st at 4:30 pm ET, dial in information below

网络直播和电话会议将于11月21日星期四下午4:30在东部时间举行,以下是拨入信息

NEWARK, CA / ACCESSWIRE / November 19, 2024 / Protagonist Therapeutics, Inc. ("Protagonist" or the "Company") today announced that the company will host a conference call and webcast to announce its oral peptide IL-17 antagonist development candidate and to share in vitro and pre-clinical proof-of-concept study results.

加利福尼亚州纽瓦克 / ACCESSWIRE / 2024年11月19日 / Protagonist Therapeutics公司("主角"或"公司")今天宣布,该公司将举办电话会议和网络直播,宣布其口服肽IL-17拮抗剂开发候选药物,并分享体外和临床前概念研究结果。

Conference Call and Webcast Details
The dial-in numbers for Protagonist's investor update on Thursday, November 21st at 4:30 pm ET are:

电话会议和网络直播细节
Protagonist投资者更新的拨入号码为东部时间11月21日下午4:30:

US-based Investors: 1-877-407-0752
International Investors: 1-201-389-0912
Conference Call ID: 13750274

美国投资者:1-877-407-0752
国际投资者:1-201-389-0912
电话会议ID:13750274

The webcast link for the event can be found here:

活动的网络直播链接在这里找到:

A replay of the presentation will be available on the Company's Investor Relations Events and Presentations webpage following the event.

演示的重播将在公司的投资者关系活动和演示网页上在活动结束后提供。

About Protagonist
Protagonist Therapeutics is a late-stage development biopharmaceutical company. Two novel peptides derived from Protagonist's proprietary discovery platform are currently in advanced Phase 3 clinical development, with New Drug Application submissions to the FDA potentially in 2025. Icotrokinra (JNJ-2113, formerly PN-235), is the first targeted oral peptide designed to selectively block the IL-23 receptor,which underpins the inflammatory response in moderate-to-severe plaque PsO and other IL-23-mediated diseases. Icotrokinra binds to the IL-23 receptor with single-digit picomolar affinity and demonstrated potent, selective inhibition of IL-23 signaling in human T cells. Icotrokinra is licensed to Johnson & Johnson and is currently in Phase 3 development for psoriasis and is nearing completion of Phase 2b development for ulcerative colitis. Following icotrokinra's joint discovery by Protagonist and Johnson & Johnson scientists pursuant to the companies' IL-23R collaboration, Protagonist was primarily responsible for development of icotrokinra through Phase 1, with Johnson & Johnson assuming responsibility for development in Phase 2 and beyond. Rusfertide, a mimetic of the natural hormone hepcidin, is currently in Phase 3 development for the rare blood disorder polycythemia vera. Rusfertide is being co-developed and will be co-commercialized with Takeda Pharmaceuticals pursuant to a worldwide collaboration and license agreement entered into in 2024 under which the Company remains primarily responsible for development through NDA filing. The Company also has a number of pre-clinical stage oral drug discovery programs addressing clinically and commercially validated targets, including IL-17, hepcidin mimetic, and anti-obesity programs.

关于主角
Protagonist Therapeutics是一家处于后期开发阶段的生物制药公司。两种新型肽来自Protagonist的专有发现平台,目前正在进行先进的第3阶段临床开发,预计将于2025年向FDA提交新药申请。Icotrokinra(JNJ-2113,原名PN-235),是首个定向口服肽,旨在选择性地阻断IL-23受体,这是中-重度斑块病和其他IL-23介导的疾病的炎症反应基础。Icotrokinra以个位数皮摩尔亲和力结合IL-23受体,并在人类T细胞中表现出对IL-23信号通路的有效、选择性抑制。Icotrokinra已授权给强生公司,目前正处于第3阶段为牛皮癣进行开发,并且即将完成第20亿期为溃疡性结肠炎进行开发。在Protagonist和强生公司的IL-23R合作框架下,Icotrokinra由共同发现,Protagonist主要负责通过第1阶段开发Icotrokinra,而强生公司则承担第2阶段及以后的开发责任。Rusfertide是天然激素肝铁蛋白的类拟物,目前正在进行罕见血液疾病红细胞增多症的第3阶段开发。Rusfertide正在与武田制药合作开发,并将根据2024年达成的全球合作和许可协议进行共同商业化,根据该协议,公司主要负责通过NDA提交进行开发。公司还有许多处于临床前阶段的口服药物发现项目,涉及临床和商业验证的靶点,包括IL-17,肝铁蛋白类拟物和抗肥胖项目。

More information on Protagonist, its pipeline drug candidates and clinical studies can be found on the Company's website at .

有关Protagonist,其管道药物候选和临床研究的更多信息可在该公司的网站上找到。

Investor Relations Contact
Corey Davis, Ph.D.
LifeSci Advisors
+1 212 915 2577
cdavis@lifesciadvisors.com

投资者关系联系方式
Corey Davis,博士。
LifeSci顾问
+1 212 915 2577
cdavis@lifesciadvisors.com

Media Contact
Virginia Amann, Founder/CEO
ENTENTE Network of Companies
virginiaamann@ententeinc.com

媒体联系
Virginia Amann,创始人/首席执行官
ENTENTE公司网络
virginiaamann@ententeinc.com

SOURCE: Protagonist Therapeutics

资料来源:protagonist therapeutics


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