Evaxion to Present Preclinical Proof-of-Concept for Precision ERV Cancer Vaccine Concept at ESMO Immuno-Oncology Congress
Evaxion to Present Preclinical Proof-of-Concept for Precision ERV Cancer Vaccine Concept at ESMO Immuno-Oncology Congress
COPENHAGEN, Denmark, December 2, 2024 - Evaxion Biotech A/S (NASDAQ: EVAX) ("Evaxion"), a clinical-stage TechBio company specializing in developing AI-Immunology powered vaccines, will present preclinical Proof-of-Concept for its precision cancer vaccine concept, targeting non-conventional ERV (endogenous retrovirus) tumor antigens shared across patients at the ESMO Immuno-Oncology Congress, taking place from December 11-13, 2024, in Geneva, Switzerland.
丹麥哥本哈根,2024年12月2日 - Evaxion Biotech A/S(納斯達克:EVAX)("Evaxion")是一家臨床階段的科技生物公司,專注於開發以人工智能-免疫學爲基礎的生物-疫苗,將在2024年12月11日至13日在瑞士日內瓦舉行的ESMO免疫-腫瘤學大會上展示其針對患者間共享的非傳統ERV(內源性逆轉錄病毒)腫瘤抗原的精準癌症疫苗概念的臨床前概念驗證。
The data to be presented stems from studies in human cells and mouse tumor models. The studies investigated human T-cell responses and mouse tumor growth inhibition induced by precision ERV vaccine targets identified using Evaxion's AI-Immunology platform.
將要展示的數據來源於對人類細胞和小鼠腫瘤模型的研究。這些研究調查了通過Evaxion的人工智能-免疫學平台識別的精準ERV疫苗靶點所誘導的人類T細胞反應和小鼠腫瘤生長抑制。
AI-Immunology can select ERV antigens for precision therapeutic cancer vaccines, offering therapeutic options for multiple specific cancer types and potentially enabling treatment for patients who are unresponsive to conventional cancer immunotherapy.
人工智能-免疫學可以選擇ERV抗原用於精準治療癌症疫苗,爲多種特定癌症類型提供治療選擇,並可能使對常規癌症免疫治療無反應的患者獲得治療。
The new concept of deploying ERVs as vaccine targets allows for designing precision cancer vaccines that could be effective across diverse immune system characteristics, making them suitable for a wide range of patients. Evaxion plans to utilize this now preclinically validated concept to design new precision vaccine candidates to complement our existing pipeline of personalized cancer vaccines.
將ERV作爲疫苗靶點的新概念使設計精準癌症疫苗成爲可能,這些疫苗可以有效地適應不同的免疫系統特徵,使其適合廣泛範圍的患者。Evaxion計劃利用這一現已獲得臨床前驗證的概念來設計新的精準疫苗候選者,以補充我們現有的個性化癌症疫苗管道。
Conference presentation details:
會議演示細節:
Abstract title: | AI-designed cancer vaccines: antigens from the dark genome are promising cancer vaccine targets |
Poster#: | 124P |
Location: | Foyer Mezzanine |
Date/Time: | December 12, 2024, at 12.30 CET/06.30 EST |
Presenter: | Daniela Kleine-Kohlbrecher, Senior Project Manager at Evaxion |
摘要標題: | 人工智能設計的癌症生物-疫苗:來自暗基因組的抗原是有前景的癌症生物-疫苗靶點 |
海報#: | 124P |
地點: | 樓中樓 |
日期/時間: | 2024年12月12日,歐洲中部時間12:30/東部標準時間06:30 |
報告人: | Evaxion高級項目經理Daniela Kleine-Kohlbrecher |
Contact information
Evaxion Biotech A/S
Mads Kronborg
Vice President, Investor Relations & Communication
+45 53 54 82 96
mak@evaxion-biotech.com
聯繫信息
Evaxion Biotech A/S
Mads Kronborg
投資者關係與通訊副總裁
+45 53 54 82 96
mak@evaxion-biotech.com
About EVAXION
Evaxion Biotech A/S is a pioneering TechBio company based upon its AI platform, AI-Immunology. Evaxion's proprietary and scalable AI prediction models harness the power of artificial intelligence to decode the human immune system and develop novel immunotherapies for cancer, bacterial diseases, and viral infections. Based upon AI-Immunology, Evaxion has developed a clinical-stage oncology pipeline of novel personalized vaccines and a preclinical infectious disease pipeline in bacterial and viral diseases with high unmet medical needs. Evaxion is committed to transforming patients' lives by providing innovative and targeted treatment options. For more information about Evaxion and its groundbreaking AI-Immunology platform and vaccine pipeline, please visit our website.
關於EVAXION
Evaxion Biotech A/S是一家基於其人工智能平台AI-Immunology的開創性TechBio公司。Evaxion的專有可擴展AI預測模型利用人工智能解碼人類免疫系統,開發了用於癌症、細菌性疾病和病毒感染的新型免疫療法。基於AI-Immunology,Evaxion已經開發出了一系列臨床前腫瘤學和感染疾病管線,並擁有高未滿足醫學需求的細菌和病毒疾病感染系列。Evaxion致力於通過提供創新和有針對性的治療選擇來改變患者的生活。有關Evaxion及其開創性的AI-免疫學平台和疫苗管線的更多信息,請訪問我們的網站。
Forward-looking statement
This announcement contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The words "target," "believe," "expect," "hope," "aim," "intend," "may," "might," "anticipate," "contemplate," "continue," "estimate," "plan," "potential," "predict," "project," "will," "can have," "likely," "should," "would," "could," and other words and terms of similar meaning identify forward-looking statements. Actual results may differ materially from those indicated by such forward-looking statements as a result of various factors, including, but not limited to, risks related to: our financial condition and need for additional capital; our development work; cost and success of our product development activities and preclinical and clinical trials; commercializing any approved pharmaceutical product developed using our AI platform technology, including the rate and degree of market acceptance of our product candidates; our dependence on third parties including for conduct of clinical testing and product manufacture; our inability to enter into partnerships; government regulation; protection of our intellectual property rights; employee matters and managing growth; our ADSs and ordinary shares, the impact of international economic, political, legal, compliance, social and business factors, including inflation, and the effects on our business from other significant geo-political and macro-economic events; and other uncertainties affecting our business operations and financial condition. For a further discussion of these risks, please refer to the risk factors included in our most recent Annual Report on Form 20-F and other filings with the U.S. Securities and Exchange Commission (SEC), which are available at www.sec.gov. We do not assume any obligation to update any forward-looking statements except as required by law.
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