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Evaxion to Present Preclinical Proof-of-Concept for Precision ERV Cancer Vaccine Concept at ESMO Immuno-Oncology Congress

Evaxion to Present Preclinical Proof-of-Concept for Precision ERV Cancer Vaccine Concept at ESMO Immuno-Oncology Congress

Evaxion將在ESMO免疫腫瘤大會上展示精準ERV癌症生物-疫苗概念的臨床前概念證明。
Evaxion Biotech ·  12/02 00:00

COPENHAGEN, Denmark, December 2, 2024 - Evaxion Biotech A/S (NASDAQ: EVAX) ("Evaxion"), a clinical-stage TechBio company specializing in developing AI-Immunology powered vaccines, will present preclinical Proof-of-Concept for its precision cancer vaccine concept, targeting non-conventional ERV (endogenous retrovirus) tumor antigens shared across patients at the ESMO Immuno-Oncology Congress, taking place from December 11-13, 2024, in Geneva, Switzerland.

丹麥哥本哈根,2024年12月2日——專門開發人工智能免疫疫苗的臨床階段TechBio公司Evaxion Biotech A/S(納斯達克股票代碼:EVAX)(「Evaxion」)將在2024年12月11日至13日舉行的ESMO免疫腫瘤學大會上展示其精準癌症疫苗概念的臨床前概念驗證,該疫苗針對患者共享的非常規ERV(內源性逆轉病毒)腫瘤抗原,在瑞士日內瓦。

The data to be presented stems from studies in human cells and mouse tumor models. The studies investigated human T-cell responses and mouse tumor growth inhibition induced by precision ERV vaccine targets identified using Evaxion's AI-Immunology platform.

將要提供的數據來自對人體細胞和小鼠腫瘤模型的研究。這些研究調查了由使用Evaxion的人工智能免疫學平台確定的精確ERV疫苗靶標引起的人類T細胞反應和小鼠腫瘤生長抑制作用。

AI-Immunology can select ERV antigens for precision therapeutic cancer vaccines, offering therapeutic options for multiple specific cancer types and potentially enabling treatment for patients who are unresponsive to conventional cancer immunotherapy.

人工智能免疫學可以爲精準的治療性癌症疫苗選擇ERV抗原,爲多種特定癌症類型提供治療選擇,並有可能爲對傳統癌症免疫療法無反應的患者提供治療。

The new concept of deploying ERVs as vaccine targets allows for designing precision cancer vaccines that could be effective across diverse immune system characteristics, making them suitable for a wide range of patients. Evaxion plans to utilize this now preclinically validated concept to design new precision vaccine candidates to complement our existing pipeline of personalized cancer vaccines.

部署ERV作爲疫苗靶標的新概念允許設計精確的癌症疫苗,這些疫苗可以有效應對不同的免疫系統特徵,使其適用於各種患者。Evaxion計劃利用這一現已通過臨床前驗證的概念來設計新的精準候選疫苗,以補充我們現有的個性化癌症疫苗產品線。

Conference presentation details:

會議演示詳情:

Abstract title: AI-designed cancer vaccines: antigens from the dark genome are promising cancer vaccine targets
Poster#: 124P
Location: Foyer Mezzanine
Date/Time: December 12, 2024, at 12.30 CET/06.30 EST
Presenter: Daniela Kleine-Kohlbrecher, Senior Project Manager at Evaxion
摘要標題: 人工智能設計的癌症疫苗:來自黑暗基因組的抗原是有希望的癌症疫苗靶標
海報 #: 124 頁
地點: 門廳夾層
日期/時間: 2024 年 12 月 12 日,歐洲中部時間 12:30 /美國東部標準時間 06.30
演示者: Evaxion 高級項目經理 Daniela Kleine-Kohlbrecher


Contact information

Evaxion Biotech A/S
Mads Kronborg
Vice President, Investor Relations & Communication
+45 53 54 82 96
mak@evaxion-biotech.com


聯繫信息
Evaxion Biotech A/S
馬茲·克倫博格
投資者關係與傳播副總裁
+45 53 54 82 96
mak@evaxion-biotech.com

About EVAXION
Evaxion Biotech A/S is a pioneering TechBio company based upon its AI platform, AI-Immunology. Evaxion's proprietary and scalable AI prediction models harness the power of artificial intelligence to decode the human immune system and develop novel immunotherapies for cancer, bacterial diseases, and viral infections. Based upon AI-Immunology, Evaxion has developed a clinical-stage oncology pipeline of novel personalized vaccines and a preclinical infectious disease pipeline in bacterial and viral diseases with high unmet medical needs. Evaxion is committed to transforming patients' lives by providing innovative and targeted treatment options. For more information about Evaxion and its groundbreaking AI-Immunology platform and vaccine pipeline, please visit our website.

關於 EVAXION
Evaxion Biotech A/S是一家基於其人工智能平台AI免疫學的開創性TechBio公司。Evaxion 專有且可擴展的人工智能預測模型利用人工智能的力量來解碼人體免疫系統,開發針對癌症、細菌性疾病和病毒感染的新型免疫療法。基於人工智能免疫學,Evaxion開發了臨床階段的新型個性化疫苗的腫瘤學產品線,以及針對未滿足大量醫療需求的細菌和病毒性疾病的臨床前傳染病管線。Evaxion致力於通過提供創新的有針對性的治療方案來改變患者的生活。有關Evaxion及其開創性的人工智能免疫學平台和疫苗管道的更多信息,請訪問我們的網站。

Forward-looking statement
This announcement contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The words "target," "believe," "expect," "hope," "aim," "intend," "may," "might," "anticipate," "contemplate," "continue," "estimate," "plan," "potential," "predict," "project," "will," "can have," "likely," "should," "would," "could," and other words and terms of similar meaning identify forward-looking statements. Actual results may differ materially from those indicated by such forward-looking statements as a result of various factors, including, but not limited to, risks related to: our financial condition and need for additional capital; our development work; cost and success of our product development activities and preclinical and clinical trials; commercializing any approved pharmaceutical product developed using our AI platform technology, including the rate and degree of market acceptance of our product candidates; our dependence on third parties including for conduct of clinical testing and product manufacture; our inability to enter into partnerships; government regulation; protection of our intellectual property rights; employee matters and managing growth; our ADSs and ordinary shares, the impact of international economic, political, legal, compliance, social and business factors, including inflation, and the effects on our business from other significant geo-political and macro-economic events; and other uncertainties affecting our business operations and financial condition. For a further discussion of these risks, please refer to the risk factors included in our most recent Annual Report on Form 20-F and other filings with the U.S. Securities and Exchange Commission (SEC), which are available at www.sec.gov. We do not assume any obligation to update any forward-looking statements except as required by law.

前瞻性陳述
本公告包含經修訂的1933年《證券法》第27A條和經修訂的1934年《證券交易法》第21E條所指的前瞻性陳述。「目標」、「相信」、「期望」、「希望」、「目標」、「打算」、「可能」、「預測」、「考慮」、「繼續」、「估計」、「計劃」、「潛力」、「預測」、「項目」、「將會」、「可能」、「可能」、「應該」、「會」、「可能」 等詞語具有相似含義的術語用於識別前瞻性陳述。由於各種因素,實際結果可能與此類前瞻性陳述所示結果存在重大差異,包括但不限於以下方面的風險:我們的財務狀況和對額外資本的需求;我們的開發工作;我們的產品開發活動以及臨床前和臨床試驗的成本和成功;使用我們的人工智能平台技術開發的任何經批准的藥品的商業化,包括候選產品的市場接受率和程度;我們對第三方的依賴,包括進行臨床測試和產品製造;我們無法建立合作伙伴關係;政府監管;保護我們的知識產權;員工事務和增長管理;我們的ADS和普通股;包括通貨膨脹在內的國際經濟、政治、法律、合規、社會和商業因素的影響,以及其他重大地緣政治和宏觀經濟事件對我們業務的影響;以及影響我們業務運營和財務狀況的其他不確定性。有關這些風險的進一步討論,請參閱我們最新的20-F表年度報告和向美國證券交易委員會(SEC)提交的其他文件中包含的風險因素,這些文件可在www.sec.gov上查閱。除非法律要求,否則我們不承擔任何更新任何前瞻性陳述的義務。

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