[text / Observer Network Zhou Yibo]
The US Centers for Disease Control and Prevention (CDC) issued a notice on Aug. 11 local time, advising pregnant women to be vaccinated against COVID-19 as soon as possible, considering that pregnant women are at greater risk of severe symptoms or premature birth after being infected with novel coronavirus, saying that vaccination will not increase the risk of miscarriage.
According to CDC data, of the 2500 women who received the mRNA vaccine before 20 weeks of pregnancy, the abortion rate was about 13%, similar to the expected abortion rate among the general population, but as of July 31, only 23% of people in the United States had received one dose of the vaccine during pregnancy.
The American College of Obstetricians and Gynecologists (ACOG) and the Maternal and Fetal Medical Association (SMFM) also strongly support vaccination for pregnant women, saying it will protect themselves, families and communities, according to ABC. However, the report also pointed out that the clinical trial of COVID-19 vaccine initially did not include pregnant women, so CDC could not issue clear safety and effectiveness guidance as quickly as other adults.
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On Aug. 11, CDC posted a message on its official website advising all people aged 12 and over to be vaccinated against COVID-19, including pregnant women, breastfeeding and those who are preparing for pregnancy.
This information shows that there is growing evidence of the safety and effectiveness of COVID-19 vaccination during pregnancy. These data indicate that the benefits of vaccination outweigh any known or potential risks of vaccination during pregnancy.
"there is no evidence that any vaccine, including the COVID-19 vaccine, will cause fertility problems in women or men."
CDC pointed out that pregnant women have a higher risk of developing severe symptoms after being infected with COVID-19 than those who are not pregnant, which can lead to hospitalization, intensive care, need to use a ventilator and even death.
In addition, compared with women who were not infected with COVID-19, women who were infected with COVID-19 had a higher risk of preterm delivery and may have a higher risk of other adverse pregnancy outcomes.
In order to demonstrate the safety and effectiveness of vaccination for pregnant women, CDC cited the post-vaccination data collected by the Vaccine adverse event reporting system (VAERS), the Vaccine Safety data Link (VSD) and the Clinical Immunization Safety Assessment Program (CISA).
The data show that among 2500 women who received the mRNA vaccine before 20 weeks of pregnancy, the abortion rate was about 13%, similar to the expected abortion rate of the general population (11% Mel 16%).
Accordingly, CDC said that scientists did not find an increased risk of miscarriage after receiving the mRNA COVID-19 vaccine during pregnancy. "these early data do not find any safety problems for vaccinated pregnant women and their babies."
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According to ABC, Sascha Ellington, an epidemiologist and head of the emergency preparedness and response team of CDC's reproductive health department, said in an interview that the benefits of vaccination for pregnant women far outweigh any potential or known risks.
"We have not found any vaccine risk for pregnancy, and we know that if you are infected with COVID-19 during pregnancy, your risk of deterioration and consequences is higher. So, for these reasons, you should be vaccinated. "
Ellington said that the low vaccination rate and the rapid spread of Delta variants have led to an increase in the number of pregnant women and hospitalizations. "given that the vaccination rate is so low, there is a lot of room to improve this level," Ellington said. and it is also possible to protect women from novel coronavirus and save lives. "
As of July 31, only 23% of people in the United States had received a single dose of the vaccine during pregnancy, according to CDC.
The American College of Obstetricians and Gynecologists (ACOG) and the Maternal and Fetal Medical Association (SMFM) also strongly support vaccination for pregnant women, both of which are non-profit organizations that study issues in the field of women's health or maternal and child health, the report said.
"ACOG recommends vaccination for pregnant women because we have evidence that thousands of reported COVID-19 patients were vaccinated safely and effectively during pregnancy, because we know that infection with COVID-19 increases the risk of serious complications in pregnant women, because judging from the current vaccination rate, people need to have confidence in the safety and protective value of COVID-19 vaccine." "pregnant women should be confident that vaccination can protect not only themselves, but also their families and communities," ACOG Chairman Martin Martin Tucker said in a statement.
However, ABC also pointed out in the report that because the clinical trial of COVID-19 vaccine initially did not include pregnant women, CDC was unable to issue clear safety and effectiveness guidance as quickly as other adults.
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A statement on the official website of the American College of Obstetricians and Gynecologists (ACOG) advising pregnant women to be vaccinated
Pfizer Inc is the main mRNA vaccine vaccinated by the American people.And Modena vaccine. It is worth noting that in January this year, the World Health Organization (WHO) issued a document advising pregnant women not to be vaccinated against Modena.
Although pregnant women have a higher risk of contracting COVID-19, such people are not recommended to use Modena vaccine unless they are at higher risk of exposure to the virus or health workers on the front line of fighting the epidemic, the article said.
In February this year, Pfizer Inc plans to recruit 4000 pregnant women from the United States, Argentina, Brazil, Canada and other countries to conduct clinical trials of the vaccine, who are required to be over 18 years old and pregnant for 24 to 34 weeks. This is also the first time a similar trial has been conducted in the United States.
During the trial, some pregnant women were given a real vaccine, while others received a placebo, and they didn't know which one they were given until they gave birth. At that time, participants who received a placebo will be vaccinated.
William Gruber (William Gruber), senior vice president of vaccine clinical research at Pfizer Inc, also said in a statement: "We are proud to conduct this study in pregnant women and continue to collect data on the safety and effectiveness of this vaccine to support important groups."
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On the question of whether pregnant women are suitable for COVID-19 vaccine, although China is cautious, it also recognizes the safety of Chinese vaccine.
In March this year, the "novel coronavirus vaccination Technical Guide (first Edition)" drafted by the novel coronavirus Vaccine working Group of the Chinese Center for Disease Control and Prevention showed that pregnant women are taboo or cautious in vaccination, and vaccination is not recommended for the time being.
However, the guide also points out that if you become pregnant after vaccination or if you are vaccinated in an unknown pregnancy, based on the understanding of the safety of COVID-19 vaccine (Beisheng, Wusheng, Kexingzhongwei, Kangxinuo, Zhifeilong Koma), it is not recommended to take special medical measures (such as termination of pregnancy) only for vaccination, and it is recommended to have a good pregnancy examination and follow-up. For women who have a pregnancy plan, there is no need to delay the pregnancy plan just because of novel coronavirus vaccination.