展览10.1

压力位协议

这个 支持协议 （这个”协议”) 自十月起订立并生效 [·]，2024 年，之前和之中 特拉华州的一家公司 Crescent Biopharma, Inc.（”公司”），特拉华州的一家公司 GlycoMimetics, Inc. （”父母”），以及下列签名的股东（”股东” 以及每位股东，公司， 还有家长 a”派对” 而且，总的来说，”各方”）的公司。此处使用的大写术语 但未另行定义应具有合并协议（定义见下文）中赋予此类术语的相应含义。

前言

鉴于，与此同时，在此文件的执行和交付之际，母公司、公司和 双子合并子公司，一家德拉瓦州的公司，父公司的全资子公司（“第一合并公司以及 双子合并子公司II，有限责任公司，一家特许有限责任公司（以下简称“第二合并子公司已进入合并及重组协议书（根据该协议条款可能不时修订或补充，该协议称为「合并协议」，根据此协议（i）第一个合并子公司将与公司合并，公司作为合并后的存续公司及股东全资子公司代表及（ii）公司将会与第二个合并子公司合并，第二个合并子公司将作为第二次合并的存续实体，根据合并协议中规定的条款及条件进行（统称为「合并”).

鉴此，截至本日，股东根据《交易所法》第13d-3条的定义，拥有公司股份的股份数如下 附录A.

鉴于， a作为鼓励母公司愿意签订合并协议的诱因，母公司要求股东进入 此协议。

现于此，双方有意被法律约束，特此协议如下：

1.            某些 定义就本合并协议所指定的含义而言，在此未另行定义的大写术语应具有合并协议中所赋予的含义。 在本协议的所有目的中，以下词语应具有以下相应的含义：

(a)"建设性 售出”表示，就任何安防而言，对该安防进行沽空，输入或取得关于该安防的衍生合约，在该安防上建立或取得期货或远期合约以交付该证券，或进行任何其他对冲或其他衍生交易，其具有直接或间接地实质改变该证券所有权的经济利益或风险的效果。

(b)            "股份意指（i）本协议成立日股东有益拥有的所有公司资本股份，（ii）本协议签署并交付之日起至结束日拥有并且有益拥有的所有额外公司资本股份，及（iii）本协议成立日股东无论是否目前可以转换、行使或交换，但直接或间接持有的所有可转换为公司资本股份的可转换票据、本票、认股权证、期权、权利或其他证券或工具。

(c)            “转移”或“转让”指任何安全性的直接或间接转让、出售、转移、投标、交换、抵押、质押或留置权，或对其设立、创建或投票产生留置权、安全利益或担保，或对其作出信托的礼物、授予或设立、或通过法律控制项或其他方式对该证券的构造性出售或其他处置（包括通过遗嘱或没有遗嘱的继承、通过国内法律令或其他法院命令，或其他法律运作），或其中的任何权利、标的或利益（包括持有人可能有的任何投票权或权力，无论该权利或权力是否通过代理人或其他方式授予），或其有益所有权，以及提出进行此类出售、转让、构造性出售或其他处置的要约，以及为实现任何上述行为而达成的任何协议、安排或了解，无论是否以书面形式。

2.            转让 及投票限制。股东向母公司和公司作出以下承诺：

(a) 除外 除非另行允许 第‎2‎ (c) 节，自本协议执行和交付之日起的期限内 并在到期日（定义见下文）到期，股东不得转让任何股东的股份，也不得公开转让 宣布打算转让其任何股份。

(b) 除非本协议另有规定，或者经有管辖权的法院或政府当局的订单另有允许或要求，股东不得进行任何可能限制股东合法权力、权限和投票权，或以其他方式阻碍或使股东无法履行本协议项下义务的行为。在不限制前述一般性规定的情况下，除了本协议及本协议另行允许的情况外，股东不得与任何人或实体订立任何有关股东持有的股份的投票协议，授予任何人或实体股份的任何代理权(可撤销或不可撤销)或授权书，将股份存入投票信托或以其他方式与任何人或实体订立任何协议或安排，该协议或安排会限制或影响股东执行及交付公司股东书面同意的合法权力、权限或权利。

尽管本协议中的其他条款相反，股东可以随时通过遗嘱或其他遗嘱文件或通过继承等方式转让股份，直接或间接地转让给股东的关联方，直接家庭成员，或者（如果股东是公司、合伙企业或其他实体）转让给股东持有的股份的受益所有人的直系家庭成员，转让给任何信托或其他实体，直接或间接地为股东或股东的直系家庭成员或（如果股东是公司、合伙企业或其他实体）为股东持有的股份数受益所有人的直系家庭成员提供直接或间接利益，或者出于遗产税或遗产规划目的，对于非自然人的股东，可以按照股东组织文件从股东向其成员、合伙人或股东进行按比例分配，从母公司根据母公司融资在收盘日期左右购买（包括母公司根据任何预资助权证转换而发行的任何母公司股份），以及根据适用法律的要求； 在每种情况下，该B类股东和/或该B类股东的家庭成员需独立控制在此类帐户、计划或信托中持有的B类普通股实时；在(i)-(v)款的情况下，转让的股份应继续受本协议约束，如果未曾是该协议的一方，则这些转让股份的适用直接受让人（如果有）在转让完成时应对母公司和公司执行并提交一份与本协议基本相同的压力位协议。¹ 在（x）款中，这些转让的股份应继续受本协议限制，在（y）款中，在转让完成时，这些转让股份的适用直接受让人（如果有）如尚未成为本协议的一方，则应向母公司和公司执行和提交与本协议基本相同的支持协议。

¹ 草稿注意事项PIPE股份在这些交易中通常被排除在这项义务之外，因为在投票时PIPE股份尚未发行。至于如果适用法律要求转让，我们可能会试图施加额外义务，但我们推定任何此类法律将覆盖在此处列明的义务。

(d) 尽管本协议中有任何相反规定，但本协议中的任何内容均不会强制股东行使任何期权或其他任何权利以取得任何公司股票。

3.            同意 投票股份。股东向公司作出以下承诺：

(a) 在截止日期（如下所定义）之前，在公司召开的任何股东大会，不论如何召集，以及每次休会或推迟和每次由公司股东书面同意的行动或批准，股东应当出席（亲自或代理），并投票，或行使其同意权，关于由股东持有的所有股份（A）赞成通过和批准并购协议，（B）赞成批准拟议交易和（C）反对任何收购提议。

(b) 如果股东不是持股的记录所有者，股东同意采取一切必要行动，以使记录所有者和任何被提名人出席（亲自或通过代理），并根据本 第3部分。

(c)            如果发生股票分割、送转或股息分配，或由于任何分拆、股权逆市回购、资本再确定、合并、重分类、再度组织、股票交换等情况对公司资本股进行任何变更，在此类事项中，“股份”应被视为包括这些股份以及所有这类股票送转和分配，以及被更换或交换为这些股份或在此类交易中收到的任何证券。

4.            仅以股东身份行使权利股东仅以其所持股份的受益者身份而订立本协议，并非以公司的董事或高管身份。本协议中的任何条款均不会限制或影响股东作为公司董事或高管的能力。

5.            不可更改的代理。 股东特此撤销（或同意撤销）其先前就其股份授予的任何代理。 如果股东未能根据本协议的规定对股份进行表决，则在有关公司股东的任何适用股东大会或根据公司股东的任何适用书面同意书之情况下，则视为股东已不可撤销地授予公司并委派公司及其书面指定的任何个人，以及他们中的每一个人，作为其代理人和全权代理人（具有替代权全权），就其名义，代表其行使表决权在公司股东的任何书面同意行动中或在公司股东召集的股东大会上就协议第3部分规定的事项中的任何一项进行表决。公司同意不会行使此处授予的代理权，目的不得超出本协议描述的目的。 除本协议另有规定外（包括下一句），股东特此确认不可撤销的代理与利益相结合，且在任何情况下均不得撤销该不可撤销代理且该不可撤销代理是经过签署并意在不可撤销的。尽管本协议的任何其他规定，此处授予的不可撤销代理将于到期日自动终止。 第 3 节，除非对任何股份另有明确声明，否则股东是公司股份的受益所有者，自由清晰，不受任何留置权益的限制（除非根据本协议、股东、公司和母公司签订的任何限制出售协议以及适用证券或其他社区财产法律下产生的留置权益的影响）；而且 (ii) 股东除公司股本和购买公司股本的权利之外，不拥有公司的任何证券。在公司股东的任何适用股东大会或根据公司股东的任何适用书面同意书之情况下 第 3 节，除非对任何股份另有明确声明，否则股东是公司股份的受益所有者，自由清晰，不受任何留置权益的限制（除非根据本协议、股东、公司和母公司签订的任何限制出售协议以及适用证券或其他社区财产法律下产生的留置权益的影响）；而且 (ii) 股东除公司股本和购买公司股本的权利之外，不拥有公司的任何证券。本协议第3部分规定的事项，且按照和一致于

6.            不 接受招揽股东同意不会直接或间接地，包括通过其任何高管、董事或代理人，采取任何公司依据并购协议第5.4节和并购协议第5.4节禁止采取的行动，特此参照并入。 必要时修改.

7.            文档和信息股东应允许，并特此授权母公司和公司在与并购及相关交易有关的所有提交给美国证券交易委员会的文件和日程安排，以及母公司或公司合理确定为必要的任何新闻发布或其他披露文件中，披露本协议的副本，股东的身份和股份所有权以及股东在本协议项下的承诺和义务性质；但母公司和公司应提前向股东提供此类文件、日程、新闻发布或其他披露文件供其审查和意见。母公司和公司均是本协议的受益方之一 第 7 条.

8.            不 行使评估权利；放弃权利。股东在此不可撤销地、无条件地(a)放弃，并同意导致或阻止行使任何评估权利、任何持异议者权利和任何类似权利（包括与此相关的任何通知要求），关于股东可能因持有股份而拥有的、或关于合并的与之相关的任何股份（包括所有根据DGCL第262条的权利）；以及(b)同意股东不会提出、发起、成立、维持、提起或自愿援助或参与任何诉讼、索赔、诉讼或法律或公正地在任何法院或在任何政府部门之前参与的行动，其中(i)挑战本协议的任何条款的有效性或试图禁止该协议的执行，或(ii)声称股东签署和交付本协议违反了股东对本公司或其他公司股东可能拥有的（或可能被指控拥有）的任何义务； 在每种情况下，该B类股东和/或该B类股东的家庭成员需独立控制在此类帐户、计划或信托中持有的B类普通股实时；，（x）股东可以为协议以独立身份作为公司董事、高管或持股人在股东自身之权利下，为所提出的针对股东的任何此类诉讼、索赔、诉讼或原本诉讼进行辩护、争议或和解，（y）前述不限制或限制股东以任何方式执法本协议及股东与本协议相关的其他协议，或以其他方式与合并有关的任何协议，包括根据合并协议条款收到合并对价的股东权利。

9.            股东的陈述与担保股东特此向母公司和公司作出以下声明和保证：

(a)            (i) 股东是公司股本中所示股份的受益所有人，所有这些股份均是股东自由清晰的，除了根据本协议可加以施加的任何留置权利，由股东、公司和母公司签订的任何限制出售协议，以及根据适用证券或其他社区财产法律产生的任何留置权利；和 (ii) 股东除了公司股本和购买公司股本的权利所示，不另外拥有公司的任何证券。 附录A （每一份均被视为股东持有，目的是（无论是否明确说明，均与任何股份有关)自由清晰，除了可能根据本协议施加的任何留置权利，由股东、公司和母公司签订的任何限制出售协议以及适用证券或其他社区财产法律下产生的任何留置权利；(ii) 股东除了公司股本和购买公司股本的权利所示，不另外拥有公司的任何证券。 第 3 节，除非对任何股份另有明确声明，否则股东是公司股份的受益所有者，自由清晰，不受任何留置权益的限制（除非根据本协议、股东、公司和母公司签订的任何限制出售协议以及适用证券或其他社区财产法律下产生的留置权益的影响）；而且 (ii) 股东除公司股本和购买公司股本的权利之外，不拥有公司的任何证券。 ），自由清晰，不受任何留置权益的限制，（除了根据本协议、股东、公司和母公司签订的任何限制出售协议的约束以及适用证券或其他社区财产法律下产生的留置权益）；而且 (ii) 股东除公司股本和购买公司股本的权利之外，不拥有公司的任何证券。 附录A），自由清晰，不受任何留置权益的限制，（除了根据本协议、股东、公司和母公司签订的任何限制出售协议的约束以及适用证券或其他社区财产法律下产生的留置权益）；而且 (ii) 股东除公司股本和购买公司股本的权利之外，不拥有公司的任何证券。 附录A.

(b) 除非本协议另有规定，股东有充分的权力和授权：(i)签订并执行本协议的条款，(ii)根据本协议中规定的方式投票支持其所持有的所有股份，无需得到其他任何个人或实体（包括任何政府机构）的同意或批准，或采取任何其他行动。在不限制前述一般性规定的前提下，股东未与任何人签订与其所持股票有关的任何投票协议（除本协议外），未向任何人提供有关其所持股份的任何（可撤销或不可撤销的）授权委托书或代理权，未将其所持股份存入投票信托或与他人签订任何限制或影响其合法投票权利的安排或协议。

本协议已由股东合法有效地签署并交付，并（假定其他各方已经获得授权、签署和交付）构成股东可依照协议条款执行的有效且具约束力的协议，但受强制执行例外的限制。股东签署并交付本协议，以及根据本协议在此做出的协议和义务的履行，不会导致任何合同条款的违反或违背或与之相冲突或构成违约，不会违反股东作为一方或受约束方参与的任何合同或（如适用）其组织文件（包括注册证书）的条款，也不会违反股东（或其任何资产）受约束或受制于的任何适用法律的规定，除非任何此类违反、违例、冲突或违约在单独或累积的情况下均不会合理地预期对股东履行本协议项下义务造成实质性损害或不利影响。

(d)            本协议由股东执行、交付和履行，不需要任何政府机构的同意、批准、授权或许可，除非没有作出或获得此类同意、批准、授权、许可、行动、申报或通知将不能或无法单独或总体上重大影响股东履行本协议项下的义务。

(e)            The Stockholder has had the opportunity to review the Merger Agreement and this Agreement with counsel of the Stockholder’s own choosing. The Stockholder has had an opportunity to review with its own tax advisors the tax consequences of the Merger and the Contemplated Transactions. The Stockholder understands that it must rely solely on its advisors and not on any statements or representations made by Parent, the Company or any of their respective agents or representatives with respect to the tax consequences of the Merger and the Contemplated Transactions. The Stockholder understands that such Stockholder (and not Parent, the Company or the Surviving Entity) shall be responsible for such Stockholder’s tax liability that may arise as a result of the Merger or the Contemplated Transactions. The Stockholder understands and acknowledges that the Company, Parent and Merger Sub are entering into the Merger Agreement in reliance upon the Stockholder’s execution, delivery and performance of this Agreement.

(f)            With respect to the Stockholder, as of the date hereof, there is no action, suit, investigation or proceeding pending against, or, to the knowledge of the Stockholder, threatened against, the Stockholder or any of the Stockholder’s properties or assets (including the Shares) that would reasonably be expected to prevent or materially delay or impair the ability of the Stockholder to perform its obligations hereunder or to consummate the transactions contemplated hereby.

10.            Certain Agreements. Each Stockholder, by this Agreement, and with respect to such Stockholder’s Shares, severally and not jointly, hereby agrees to terminate, subject to the occurrence of, and effective immediately prior to, the First Effective Time any rights under any letter agreement providing for redemption rights, put rights, purchase rights, information rights, rights to consult with and advise management, inspection rights, preemptive rights, board of directors observer rights or rights to receive information delivered to the board of directors or other similar rights not generally available to stockholders of the Company between the Stockholder and the Company, but excluding, for the avoidance of doubt, any rights the Stockholder may have that relate to any indemnification, commercial, development or employment agreements or arrangements between such Stockholder and the Company or any subsidiary of the Company, which shall survive in accordance with their terms. Each Stockholder hereby terminates and waives all rights of first refusal, redemption rights and rights of notice of the Merger and the other transactions contemplated by the Merger Agreement, effective as of immediately prior to, and contingent upon, the First Effective Time.

11.            Termination. This Agreement shall terminate and shall cease to be of any further force or effect as of the earliest of (a) such date and time as the Merger Agreement shall have been terminated pursuant to the terms thereof as in effect on the date of this Agreement (and without giving effect to any amendments thereto unless consented to by the Stockholder), (b) the First Effective Time and (c) the time this Agreement is terminated upon the written agreement of the Stockholder, the Company and Parent (the “Expiration Date”); provided, however, that (i) Section ‎12 shall survive the termination of this Agreement and (ii) the termination of this Agreement shall not relieve any Party from any liability for any material and willful breach of this Agreement prior to the First Effective Time.

12.            Miscellaneous Provisions.

(a)            Amendments. No amendment of this Agreement shall be effective against any Party unless it shall be in writing and signed by each of the Parties.

(b)            Entire Agreement; Counterparts; Exchanges by Electronic Transmission or Facsimile. This Agreement constitutes the entire agreement between the Parties and supersedes all other prior agreements, arrangements and understandings, both written and oral, among the Parties with respect to the subject matter hereof. This Agreement may be executed in several counterparts, each of which shall be deemed an original and all of which shall constitute one and the same instrument. The exchange of a fully executed Agreement (in counterparts or otherwise) by all Parties by facsimile or electronic transmission in PDF format shall be sufficient to bind the Parties to the terms and conditions of this Agreement.

(c)            Applicable Law; Jurisdiction. This Agreement shall be governed by, and construed in accordance with, the laws of the State of Delaware, regardless of the laws that might otherwise govern under applicable principles of conflicts of laws. In any action or proceeding between any of the Parties arising out of or relating to this Agreement, each of the Parties: (i) irrevocably and unconditionally consents and submits to the exclusive jurisdiction and venue of the Court of Chancery of the State of Delaware or, to the extent such court does not have subject matter jurisdiction, the Superior Court of the State of Delaware or the United States District Court for the District of Delaware, (ii) agrees that all claims in respect of such action or proceeding shall be heard and determined exclusively in accordance with clause (i) of this Section ‎12‎‎(c), (iii) waives any objection to laying venue in any such action or proceeding in such courts, (iv) waives any objection that such courts are an inconvenient forum or do not have jurisdiction over any Party, (v) agrees that service of process upon such Party in any such action or proceeding shall be effective if notice is given in accordance with Section ‎12‎(h) of this Agreement and (vi) irrevocably and unconditionally waives the right to trial by jury.

(d)            Assignment. This Agreement shall be binding upon, and shall be enforceable by and inure solely to the benefit of, the Parties and their respective successors and permitted assigns; provided, however, that neither this Agreement nor any of a Party’s rights or obligations hereunder may be assigned or delegated (except pursuant to the Merger) by such Party without the prior written consent of the other Parties, and any attempted assignment or delegation of this Agreement or any of such rights or obligations by such Party without the other Parties’ prior written consent shall be void and of no effect.

(e)            No Third-Party Rights. Nothing in this Agreement, express or implied, is intended to or shall confer upon any Person any right, benefit or remedy of any nature whatsoever under or by reason of this Agreement.

(f)             Severability. Any term or provision of this Agreement that is invalid or unenforceable in any situation in any jurisdiction shall not affect the validity or enforceability of the remaining terms and provisions of this Agreement or the validity or enforceability of the offending term or provision in any other situation or in any other jurisdiction. If a final judgment of a court of competent jurisdiction declares that any term or provision of this Agreement is invalid or unenforceable, the Parties agree that the court making such determination shall have the power to limit such term or provision, to delete specific words or phrases or to replace such term or provision with a term or provision that is valid and enforceable and that comes closest to expressing the intention of the invalid or unenforceable term or provision, and this Agreement shall be valid and enforceable as so modified. In the event such court does not exercise the power granted to it in the prior sentence, the Parties agree to replace such invalid or unenforceable term or provision with a valid and enforceable term or provision that will achieve, to the extent possible, the economic, business and other purposes of such invalid or unenforceable term or provision.

(g)            Specific Performance. Except as otherwise provided herein, any and all remedies herein expressly conferred upon a Party will be deemed cumulative with and not exclusive of any other remedy conferred hereby, or by law or equity upon such Party, and the exercise by a Party of any one remedy will not preclude the exercise of any other remedy. The Parties agree that irreparable damage for which monetary damages, even if available, would not be an adequate remedy, would occur in the event that any of the provisions of this Agreement were not performed in accordance with their specific terms (including failing to take such actions as are required of it hereunder to consummate this Agreement) or were otherwise breached. It is accordingly agreed that the Parties shall be entitled to an injunction or injunctions to prevent breaches of this Agreement and to enforce specifically the terms and provisions hereof the Court of Chancery of the State of Delaware or, to the extent such court does not have subject matter jurisdiction, the Superior Court of the State of Delaware or the United States District Court for the District of Delaware, this being in addition to any other remedy to which they are entitled at law or in equity, and each of the Parties waives any bond, surety or other security that might be required of any other Party with respect thereto. Each of the Parties further agrees that it will not oppose the granting of an injunction, specific performance or other equitable relief on the basis that any other Party has an adequate remedy at law or that any award of specific performance is not an appropriate remedy for any reason at law or in equity.

(h)            Notices. All notices and other communications hereunder shall be in writing and shall be deemed duly delivered (i) one (1) Business Day after being sent for next Business Day delivery, fees prepaid, via a reputable international overnight courier service, (ii) upon delivery in the case of delivery by hand or (iii) on the date delivered in the place of delivery if sent by email or facsimile (with a written or electronic confirmation of delivery) prior to 6:00 p.m. (New York City time), otherwise on the next succeeding Business Day, (A) if to the Company or Parent, to the address, electronic mail address or facsimile provided in Section 11.7 of the Merger Agreement, including to the persons designated therein to receive copies; and/or (B) if to the Stockholder, to the Stockholder’s address, electronic mail address or facsimile shown below Stockholder’s signature to this Agreement.

(i)             Confidentiality. Except to the extent required by applicable Law or regulation, the Stockholder shall hold any non-public information regarding the Company, this Agreement, the Merger Agreement and the Merger in strict confidence and shall not divulge any such information to any third person until the Company and Parent have publicly disclosed their entry into the Merger Agreement and this Agreement; provided, however, that the Stockholder may disclose such information to its Affiliates, attorneys, accountants, consultants, and other advisors (provided that such Persons are subject to confidentiality obligations at least as restrictive as those contained herein). Neither the Stockholder nor any of its Affiliates (other than the Company, whose actions shall be governed by the Merger Agreement), shall issue or cause the publication of any press release or other public announcement with respect to the Company, this Agreement, the Merger, the Merger Agreement or the other transactions contemplated hereby or thereby without the prior written consent of the Company and Parent, except as may be required by applicable Law in which circumstance such announcing Party shall make reasonable efforts to consult with the Company and Parent to the extent practicable.

(j)             Interpretation. The words “hereof,” “herein” and “hereunder” and words of like import used in this Agreement shall refer to this Agreement as a whole and not to any particular provision of this Agreement. The captions herein are included for convenience of reference only and shall be ignored in the construction or interpretation hereof. References to Sections and Appendixes are to Sections and Appendixes of this Agreement unless otherwise specified. Any capitalized terms used in any Appendix but not otherwise defined therein shall have the meaning as defined in this Agreement. Any singular term in this Agreement shall be deemed to include the plural, and any plural term the singular, the masculine gender shall include the feminine and neuter genders; the feminine gender shall include the masculine and neuter genders; and the neuter gender shall include masculine and feminine gender. Whenever the words “include,” “includes” or “including” are used in this Agreement, they shall be deemed to be followed by the words “without limitation,” whether or not they are in fact followed by those words or words of like import. The word “or” is not exclusive. “Writing,” “written” and comparable terms refer to printing, typing and other means of reproducing words (including electronic media) in a visible form. References to any agreement or Contract are to that agreement or Contract as amended, modified or supplemented from time to time in accordance with the terms hereof and thereof. References to any Person include the successors and permitted assigns of that Person. References to any statute are to that statute and to the rules and regulations promulgated thereunder, in each case as amended, modified, re-enacted thereof, substituted, from time to time. References to “$” and “dollars” are to the currency of the United States. All accounting terms used herein will be interpreted, and all accounting determinations hereunder will be made, in accordance with GAAP unless otherwise expressly specified. References from or through any date shall mean, unless otherwise specified, from and including or through and including, respectively. All references to “days” shall be to calendar days unless otherwise indicated as a “Business Day.” Except as otherwise specifically indicated, for purposes of measuring the beginning and ending of time periods in this Agreement (including for purposes of “Business Day” and for hours in a day or Business Day), the time at which a thing, occurrence or event shall begin or end shall be deemed to occur in the Eastern time zone of the United States. The Parties agree that any rule of construction to the effect that ambiguities are to be resolved against the drafting Party shall not be applied in the construction or interpretation of this Agreement.

[Remainder of Page Left Intentionally Blank]

IN WITNESS WHEREOF, the undersigned have caused this Agreement to be duly executed as of the date first above written.

COMPANY:

Crescent Biopharma, Inc.

[Signature Page to Company Stockholder Support Agreement]

Parent:

GlycoMimetics, Inc.,

[Signature Page to Company Stockholder Support Agreement]

[STOCKHOLDER],

in his/her capacity as the Stockholder:

[Signature Page to Company Stockholder Support Agreement]

Appendix A