222.51MMarket Cap-1.53P/E (TTM)
6.440High5.680Low889.18KVolume5.680Open5.760Pre Close5.47MTurnover3.96%Turnover RatioLossP/E (Static)36.24MShares20.21052wk High2.93P/B137.87MFloat Cap3.61052wk Low--Dividend TTM22.46MShs Float43.690Historical High--Div YieldTTM13.19%Amplitude2.840Historical Low6.152Avg Price1Lot Size
Trytosaveabit OP : Preliminary data supports BMF-500's potential as a transformative therapy for patients with FLT3 mutated relapsed or refractory (R/R) acute leukemia
BMF-500 showed a favorable safety and tolerability profile, with no dose-limiting toxicities observed across all dose levels
Pharmacokinetic and pharmacodynamic data confirmed on-target FMS-like tyrosine kinase 3 (FLT3) inhibition, demonstrating dose-proportional activity and good compartmental penetration
Preliminary Phase I data for BMF-500 in R/R acute leukemia patients with FLT3 gene mutations having failed gilteritinib indicated clinical activity with evidence of responses, including a first complete response with incomplete hematologic recovery (CRi) and reductions in bone marrow blasts in 5 of 6 of the evaluable FLT3 mutated patients