5.05Open5.05Pre Close0 Volume4.12K Open Interest10.00Strike Price0.00Turnover483.75%IV19.38%PremiumDec 20, 2024Expiry Date3.86Intrinsic Value100Multiplier8DDays to Expiry1.19Extrinsic Value100Contract SizeAmericanOptions Type-0.6149Delta0.0845Gamma1.31Leverage Ratio-0.1033Theta-0.0017Rho-0.80Eff Leverage0.0036Vega
Trytosaveabit OP : Preliminary data supports BMF-500's potential as a transformative therapy for patients with FLT3 mutated relapsed or refractory (R/R) acute leukemia
BMF-500 showed a favorable safety and tolerability profile, with no dose-limiting toxicities observed across all dose levels
Pharmacokinetic and pharmacodynamic data confirmed on-target FMS-like tyrosine kinase 3 (FLT3) inhibition, demonstrating dose-proportional activity and good compartmental penetration
Preliminary Phase I data for BMF-500 in R/R acute leukemia patients with FLT3 gene mutations having failed gilteritinib indicated clinical activity with evidence of responses, including a first complete response with incomplete hematologic recovery (CRi) and reductions in bone marrow blasts in 5 of 6 of the evaluable FLT3 mutated patients