2.70Open2.70Pre Close1 Volume3.50K Open Interest7.50Strike Price270.00Turnover497.95%IV14.89%PremiumDec 20, 2024Expiry Date1.86Intrinsic Value100Multiplier6DDays to Expiry0.84Extrinsic Value100Contract SizeAmericanOptions Type-0.5559Delta0.1118Gamma2.09Leverage Ratio-0.1251Theta-0.0008Rho-1.16Eff Leverage0.0028Vega
Trytosaveabit OP : Preliminary data supports BMF-500's potential as a transformative therapy for patients with FLT3 mutated relapsed or refractory (R/R) acute leukemia
BMF-500 showed a favorable safety and tolerability profile, with no dose-limiting toxicities observed across all dose levels
Pharmacokinetic and pharmacodynamic data confirmed on-target FMS-like tyrosine kinase 3 (FLT3) inhibition, demonstrating dose-proportional activity and good compartmental penetration
Preliminary Phase I data for BMF-500 in R/R acute leukemia patients with FLT3 gene mutations having failed gilteritinib indicated clinical activity with evidence of responses, including a first complete response with incomplete hematologic recovery (CRi) and reductions in bone marrow blasts in 5 of 6 of the evaluable FLT3 mutated patients