Here are the top gap ups and downs for the stocks with a market cap above $5 billion after market closed (gaps range from large to small):
Gap Ups
1. $Vertiv Holdings (VRT.US)$ - up 18.6%
2. $Erie Indemnity (ERIE.US)$ - up 8.7%
3. $Aspen Technology (AZPN.US)$ - up 6.5%
4. $Penske Automotive (PAG.US)$ - up 5.1%
5. $Humana (HUM.US)$ - up 3.7%
6. $Teva Pharmaceutical Industries (TEVA.US)$ - up 3.7%
7. $Encompass Health (EHC.US)$ - up 3.0%
8. $Emerson Electric (EMR.US)$ - up 2.8...

$Driven Brands (DRVN.US)$ bought

$Driven Brands (DRVN.US)$ I'm watching you

Gapping up
In reaction to earnings/guidance:
• $Planet Labs PBC (PL.US)$ +11.3%, $Core & Main (CNM.US)$ +6.1%, $Regal Rexnord (RRX.US)$ +2% (reaffirms outlook), $Oracle (ORCL.US)$ +1.6%
Other news:
• $Akero Therapeutics (AKRO.US)$ +93.2% (reports Phase 2b HARMONY Study)
• $Akouos (AKUS.US)$ +10.3% (FDA clears IND application to initiate a Phase 1/2 first in human pediatric clinical trial of AK-OTOF)
• $Catalyst Pharmaceuticals (CPRX.US)$ +7.7...

Gainers:
In reaction to earnings/guidance:
• $Teva Pharmaceutical Industries (TEVA.US)$ +24%(also announces agreement for opioids settlement), $Enphase Energy (ENPH.US)$ +9.5%, $Spotify Technology (SPOT.US)$ +9.2%, $RPC Inc (RES.US)$ +8.5%, $Chipotle Mexican Grill (CMG.US)$ +8.2%, $Manhattan Associates (MANH.US)$ +8.1%, $Hilton Worldwide (HLT.US)$ +6.7%, $ChampionX (CHX.US)$ +6.1%, $Mr. Cooper Group (COOP.US)$ +5.7%, $Constellium (CSTM.US)$ +5.5%, $Boston Scientific (BSX.US)$ +5.4%,...