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    Jaguar8
    Jaguar8
    Oct 23 08:00
    NEWS
    $Kronos Bio (KRON.US)$
    Kronos Bio Data Presentation at EORTC-NCI-AACR Symposium Highlights the Importance of p300 KAT Inhibition in HPV-Driven Tumors
    Kronos Bio (NASDAQ: KRON) presented preclinical data from its p300 KAT inhibitor program for HPV-driven tumors at the EORTC-NCI-AACR Symposium. The research demonstrates that their p300 KAT inhibitor, KB-9558, effectively suppresses HPV oncogenes E6 and E7, which are critical for tumor growth. The inhibition leads to restoration of p53 and Rb tu...
    Jaguar8
    Jaguar8
    Oct 9 09:40
    NEWS
    $Kronos Bio (KRON.US)$
    Kronos Bio to Present Data at the EORTC-NCI-AACR Symposium that Supports p300 KAT Inhibition in HPV-Driven Tumors
    Kronos Bio (Nasdaq: KRON) will present preclinical data on its p300 KAT inhibitor program for HPV-driven tumors at the EORTC-NCI-AACR Symposium in Barcelona, Spain, from October 23-25, 2024. The company's p300 KAT inhibitor, KB-9558, shows promise in targeting HPV-driven cancers by selectively inhibiting viral oncoproteins E6 and E7.
    Key findings include:
    HP...
    Jaguar8
    Jaguar8
    Oct 7 07:55
    NEWS
    $Kronos Bio (KRON.US)$
    Kronos Bio Announces Selection of Autoimmune Development Candidate for Sjögren’s Disease
    Kronos Bio has announced the selection of KB-7898, a p300 KAT inhibitor, as its first development candidate for autoimmune diseases, specifically targeting Sjögren’s disease. This candidate stems from Kronos Bio's proprietary discovery engine, which decodes complex transcription factor regulatory networks.
    Preclinical data for KB-7898 will be presented at ACR Convergence 2024. The d...
    Jaguar8
    Jaguar8
    Sep 25 07:56
    NEWS
    $Kronos Bio (KRON.US)$
    Kronos Bio to Present Data at ACR Convergence 2024 to Support p300 KAT Inhibition as an Approach to Anti-Inflammatory Therapy
    Kronos Bio (Nasdaq: KRON) will present preclinical data from its p300 KAT inhibitor program for autoimmune indications at ACR Convergence 2024 in Washington, DC. The presentation, scheduled for November 18, 2024, will showcase how p300 KAT inhibitionmodulates multiple pro-inflammatory signaling pathways in chronic inflammatory diseases.
    The compa...
    Trytosaveabit
    Trytosaveabit
    Sep 23 08:00
    Update
    $Kronos Bio (KRON.US)$ Kronos Bio Highlights Data at AACR Ovarian Cancer Research Symposium that Supports Clinical Evaluation of Istisociclib in Advanced Ovarian Cancer
    4 MINUTES AGO, 8:55 AM EDT
    VIA GLOBENEWSWIRE
    – New data show istisociclib (KB-0742) triggered cell death in preclinical ovarian cancer models of platinum and PARP-inhibitor (PARPi) resistance –
    New PK/PD results demonstrate that istisociclib given at 80mg on a 4 days on/3 days off schedule resulted in sustained downregulati...
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